Boston Children's Hospital

The North lab aims to harness hematopoietic stem cells for the treatment of hematologic disease by making it possible to efficiently expand or produce them in culture.

Hematopoietic stem cells (HSCs) give rise to each of the blood lineages present...

The muscular dystrophies are progressive disorders of striated muscle leading to breakdown of muscle integrity. Underlying this clinical presentation there is considerable genetic heterogeneity with the X-chromosomal recessive Duchenne and Becker forms...

The goal of Jordan Kreidberg's research is to understand the genetic mechanisms of organogenesis, with a focus on the urogenital system.

The Kreidberg lab aims to:

• Understand the inductive mechanisms of early organ development;
• Define regulatory interactions...

The Kim Lab has pioneered the use of stem cell biology approaches for the study of adult lung progenitor cells and lung cancer.

Through a combination of mouse genetics and cell biology, Kim has developed tools to identify and characterize cells with...

Alan Cantor aims to understand the gene regulatory mechanisms involved in normal blood cell development, and to understand how their dysregulation leads to human blood disorders.

The Cantor lab is focused on further elucidating the transcriptional...

The Camargo laboratory focuses on the study of adult stem cell biology, organ size regulation, and cancer.

Despite fantastic progress in developmental biology research over the past decade, one aspect of development and tissue homeostasis for which very...

Research in the Burns Lab focuses on cardiovascular development and regeneration.

Cardiovascular diseases represent the number one cause of morbidity and mortality worldwide, affecting a broad spectrum of ages from babies that are born with congenital...

David Breault's research has exploited the fact the mouse telomerase (mTert) is a biomarker for embryonic and tissue stem cells. He has developed a streamlined technique for isolating and characterizing adult stem cells from a variety of tissues using...

The Agarwal lab aims to develop innovative therapies – using novel medications or a patient's own cells - for patients with genetic blood disorders.

Certain genetic disorders cause widespread disease in the body, but the principle reason for illness and...