Blood Diseases

Our laboratory is interested in the transcriptional regulation of normal blood cell development and leukemia. All blood cells arise from a small population of hematopoietic stem cells (HSCs) that have the capacity to, both, self-renew and mature stepwise...

Alan Cantor aims to understand the gene regulatory mechanisms involved in normal blood cell development, and to understand how their dysregulation leads to human blood disorders.

The Cantor lab is focused on further elucidating the transcriptional...

Daniel Tenen is a leader in gene regulation in both normal differentiation and cancer, with a focus on leukemia, lung cancer, and liver cancer.

Dr. Tenen's laboratory focuses on transcription factors and gene regulation, and their relationship to...

The Agarwal lab aims to develop innovative therapies – using novel medications or a patient's own cells - for patients with genetic blood disorders.

Certain genetic disorders cause widespread disease in the body, but the principle reason for illness and...

The Scadden laboratory focuses on blood, in particular the regulation of the hematopoietic stem cell by its microenvironment or niche. Their goal is to make bone marrow transplants safer and easier for both patients and donors.

Using a combination of...