In the Clinic

The Ritz lab seeks to distinguish graft-versus-leukemia (GVL) response from graft-versus-host disease (GVHD) and to develop new methods for selectively enhancing GVL.

Allogeneic hematopoietic stem cell transplantation (HSCT) is widely used in the treatment...

The Rajagopal lab focuses on organ regeneration and the application of developmental biology to human disease. They utilize the lung as a model system, in part due to the abundance of respiratory diseases of unknown causes and without cures.

The lung is...

The Pu laboratory studies the regulation of gene expression in heart development and heart failure with the goal of applying their new knowledge towards regenerative approaches to congenital and acquired heart disease.

Research in William T. Pu's...

Research in the Polyak laboratory is dedicated to the study of human breast cancer with the goal of dissecting tumor evolution and use this information to improve the clinical management of breast cancer patients. 

Main areas of interests are: (1) breast...

The Orkin laboratory has been involved in the study of blood disorders for more than 4 decades. Research of the group has examined the development and function of the blood system, the relationship between cancer and stem cells, and the mechanisms...

Dr. Notarangelo's research focuses of the characterization of the molecular and cellular bases of congenital immunodeficiencies as illustrated through the study of human patients and of suitable animal models. In particular, his lab is actively involved...

Our goal is to understand how naturally occurring human genetic variation protects (or predisposes) some people to cardiovascular and metabolic disease—the leading cause of death in the world—and to use that information to develop therapies that can...

The Marasco Lab is actively working on antibody discovery for COVID-19. See their COVID-19 page to learn more.

The Marasco lab focuses on the treatment of emerging infectious diseases and cancer. Located in the Department of Cancer Immunology and...

The MacRae lab is focused on understanding the genetic contribution to common cardiovascular disease using human studies and complementary high-throughput biology in the zebrafish.

Our lab is interested in the role of functional inputs such as mechanical...

The Macklis lab seeks to apply developmental controls toward brain and spinal cord regeneration and directed differentiation for therapeutic and mechanistic screening.

Research in the Macklis lab is directed toward both

1. understanding molecular controls...