2015

The Harvard Stem Cell Institute (HSCI) invites applications for seed grant funding for its 2016 cycle. The purpose of this program is to provide early funding for innovative projects in the field of stem cell & regenerative biology. While proposals at all...

Researchers at Harvard Stem Cell Institute suppressed the CAF1 gene to create colonies of induced pluripotent stem cell (iPS cells) at greater speeds and efficiencies . Photo courtesy of Sihem Chaloufi. Scientists identify a molecular key that helps...

Building on earlier work in which they disproved neurobiology dogma by “reprogramming” neurons — turning one form of neuron into another — in the brains of living animals, Harvard Stem Cell Institute researchers have now shown that the networks of...

Researchers uncover diverse subtypes of serotonin-producing neurons By Stephanie Dutchen, HMS Writer/Editor It used to be enough to call a serotonergic neuron a serotonergic neuron. These brain cells make the neurotransmitter serotonin, which helps...

HSCI researchers made artificial stem cells, or induced pluripotent stem cells (iPSCs), from embryonic stem cells, then turned those iPSCs into the neural cells pictured here. Photo courtesy of Jiho Choi. Experimental "trick" lets researchers compare...

Mini-kidney organoid (2 mm dimaeter) grown from pluripotent stem cells. Harvard Stem Cell Institute (HSCI) researchers at Brigham and Women’s Hospital (BWH) have combined cutting-edge, gene-editing techniques with stem cell science to for the first time...

Researchers modeled kidney development and injury in kidney organoids (shown here), demonstrating that the organoid culture system can be used to study mechanisms of human kidney development and toxicity. Photo courtesy of Ryuji Morizane. New technique...

The Harvard Stem Cell Institute (HSCI) invites applications for Pilot Grant funding for 2015 under the NIH-funded P01 grant “Dissecting the establishment and regulation of human pluripotency” (PI Alexander Meissner, Harvard Department of Stem Cell and...

In the right-hand picture, an SMA mouse treated with guanabenz, a compound known to reduce cellular stress, shows healthy junctions between muscle cells (red) and motor nerve fibers (green). In contrast, the untreated SMA mouse (left) has lost its nerve...