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2014

Content tagged with 2014

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A pill to shed fat?

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Harvard researchers have created a system using human stem cells to screen for compounds that have the potential to turn white, or “bad,” fat cells into brown, or “good,” fat cells. Pictured are human pluripotent stem cell-derived fat cells. (Photo Credit...

Reprogramming cells, long term

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Joe Zhou, an associate professor in Harvard’s Department of Stem Cell and Regenerative Biology (Photo Credit: B. D. Colen) By B. D. Colen, Harvard Staff Writer Harvard Stem Cell Institute (HSCI) researchers at five different Harvard departments and...

An unexpected function for phagocytes

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Cells that are the body's first defense against infection may play role in developing embryo 2013 HSCI Internship Program participant Isaura Frost, who worked on this project, with her mentor postdoctoral fellow Virginie Esain, PhD, at the HSCI intern...

Pain in a dish

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Turning skin cells into pain-sensing neurons Human noxious stimulus detecting sensory neurons produced by converting skin cells with a set of five genes to this new fate—enabling study of "pain"in a dish. (Credit: Elizabeth Buttermore, PhD) After more...

A case study for casual collaboration

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Annual symposium drives innovative research between CIRM-HSCI scientists The organizers of this year’s Harvard Stem Cell Institute/ California Institute for Regenerative Medicine Junior Faculty Symposium knew that it was time to rebrand. The 40 regulars...

The cellular origin of fibrosis

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Rare stem cells (in red) that give rise to scar-tissue secreting myofibroblast cells, here found near the blood vessels of a mouse kidney (in green). (Credit: Rafael Kramann, MD) Harvard team identifies rare stem cells that give rise to chronic tissue...

New strategy to improve stem cell transplantation

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Research addresses hurdles to future transplant-based, gene-editing therapies that could help people with genetic blood diseases HSCI scientists at Harvard's Department of Stem Cell and Regenerative Biology and the Massachusetts General Hospital Center...