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Research

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Our research program bridges gaps in traditional funding to encourage bold thinking and nurture scientific careers. We strive to create a highly collaborative environment with multiple channels of interaction, which gives rise to new ideas, new programs...

Amy Wagers, Ph.D.

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Amy Wagers seeks to change the way we repair our tissues after an injury. 

Her research focuses on defining the factors and mechanisms that regulate the migration, expansion, and regenerative potential of adult blood-forming and muscle-forming stem cells.

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Muscular dystrophy collaboration aims to correct muscle stem cell DNA

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HSCI research receives support from Sarepta to advance in-vivo genome editing toward prospective therapy HSCI researchers led by Amy Wagers, Ph.D. are embarking on a major study of Duchenne muscular dystrophy (DMD). The project aims to use in vivo genome...

How a small fish could lead to better strategies to repair tendon tears

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This post originally appeared on the Mass General Research Institute blog Autumn means the return of fall sports such as soccer and football. Unfortunately, it can also lead to a new wave of sports-related injuries such as tendon tears. Last month, New...

Improving skin organoids

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HSCI researchers develop a more accurate model of human skin with fat, nerves, and hair For more than 40 years, scientists have been recreating human skin in the lab. Yet all of these models have lacked many of the component cells and structures of normal...

Student science rendezvous in space

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Current and former HIP interns launch research projects on the same rocket by Hannah L. Robbins Mosquitos buzzed in the warm, night air at Cape Canaveral, Florida. Half past midnight on July 18, and still the spectators could not detect activity on the...

Harvard Stem Cell Institute (HSCI)

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Human muscle stem cell therapy gets help from zebrafish

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Harvard Stem Cell Scientists have discovered that the same chemicals that stimulate muscle development in zebrafish can also be used to differentiate human stem cells into muscle cells in the laboratory, an historically challenging task that, now overcome...

An HSCI approach to rhabdomyosarcoma

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Rhabdomyosarcoma is a rare childhood cancer that arises in muscle stem cells. Between 250-350 cases are treated each year. The disease most commonly begins as a noticeable swelling in the arms, legs, head, neck, or groin, and is treated by surgical...

Startups

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A key part of our mission is to move discoveries from the laboratory into the market. One way we achieve this is through our faculty, who form startup companies based on their work. The following companies have been founded or co-founded by HSCI...

Faculty

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HSCI is a network of over 350 faculty across Harvard who are harnessing the power of stem cells to find new treatments and cures for disease. HSCI has been breaking down barriers to collaboration in stem cell science since 2004. We have been instrumental...

Business of Regenerative Medicine 2019: Conference Summary

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The 12th annual Business of Regenerative Medicine conference, hosted by the Harvard Stem Cell Institute on 15-16 July 2019, examined how to define and create “value” in a field set to transform human health. At the 12th annual Business of Regenerative...