Paola Arlotta

By Lydialyle Gibson This article originally appeared in Harvard Magazine. Paola Arlotta is searching for the words to describe the clusters of cells, incubating quietly in a small room next to her laboratory, that have profoundly reshaped her life’s work...

A single-cell analysis of 3D models of the human cerebral cortex suggests they can be used to study important brain processes that have been difficult to investigate Adapted from the Broad Institute By Allessandra DiCorato Organoids are carefully grown...

Harvard and Broad researchers use 3D, miniature models of the human brain to advance disease understanding By Jessica Lau Autism spectrum disorder has been associated with hundreds of different genes, but how these distinct genetic mutations converge on a...

Harvard and Broad researchers combine single-cell genomic technologies to map the mouse cortex Researchers at Harvard University and the Broad Institute of MIT and Harvard have created the first detailed atlas of a critical region of the developing mouse...

Researchers identify a new level of complexity in how the brain responds to stimuli By Jessica Lau Harvard researchers have discovered a new way that the brain responds to stimuli, with different types of neurons using myelin in different ways. By...

Scientists apply the “Perturb-Seq” method to a living organism for the first time Scientists at Harvard University, the Broad Institute of MIT and Harvard, and MIT have developed a technology to investigate the function of many different genes in many...

Precise control over neuron growth paves the way for repairing injuries, improving brain models By Jessica Lau Harvard Stem Cell Institute researchers have developed an engineering technique to precisely control the direction that neurons grow their axons...

Reproducible, miniature 3D models of human brain tissue open up new frontiers in neuroscience Summary Research led by scientists at Harvard and the Broad Institute has optimized the process of making human brain ‘organoids’ – miniature 3D organ models –...

HSCI, a network of the nation’s top stem cell and regenerative medicine researchers, gathers to exchange ideas and forge new collaborations to advance biomedical research. Summary 2018 gathering of stem cell scientists provided rich ground for knowledge...

Scientists have found ways of culturing organ-specific tissue from stem cells that could change the way diseases are studied and treated. By Javier Barbuzano Imagine the possibility of creating individualized, complex collections of cells that bear a...