Lee Rubin

Lee Rubin, Professor of Stem Cell and Regenerative Biology and leading scholar of neurodegenerative disease, has been named the next faculty co-director of the Harvard Stem Cell Institute (HSCI). Effective this spring, he joins current co-director David...

Researchers awarded funding by the Simons Collaboration on Plasticity and the Aging Brain Two HSCI scientists have joined the Simons Collaboration on Plasticity and the Aging Brain. Funded by the Simons Foundation, the effort has pledged $42 million over...

HSCI researchers take a single-cell dive into how aging affects gene expression in the mouse brain By Jessica Lau HSCI researchers have created a highly detailed map of how the mouse brain changes with age. Using single-cell sequencing, the scientists...

Scientists have found ways of culturing organ-specific tissue from stem cells that could change the way diseases are studied and treated. By Javier Barbuzano Imagine the possibility of creating individualized, complex collections of cells that bear a...

SMN protein (red) is necessary for the survival of spinal cord neurons (motor neurons) responsible for breathing and all movement. Harvard researchers have found a compound that stabilized this protein in mouse and human motor neurons. This may lead to...

In the right-hand picture, an SMA mouse treated with guanabenz, a compound known to reduce cellular stress, shows healthy junctions between muscle cells (red) and motor nerve fibers (green). In contrast, the untreated SMA mouse (left) has lost its nerve...

Turning skin cells into pain-sensing neurons Human noxious stimulus detecting sensory neurons produced by converting skin cells with a set of five genes to this new fate—enabling study of "pain"in a dish. (Credit: Elizabeth Buttermore, PhD) After more...

Lee Rubin, PhD, and Amy Wagers, PhD, (below) of the Harvard Stem Cell Institute provide more evidence that a protein known as GDF11 reverses signs of aging in mice. (Credit: B.D. Colen/Harvard University) Harvard stem cell researchers advance...