Diabetes Program

HSCI researchers find drug that protects insulin-producing cells from stress and autoimmune attack To treat type 1 diabetes, scientists have learned how to grow large volumes of insulin-producing beta cells to replace the ones destroyed by the patient’s...

HSCI scientists have combined organ-on-a-chip and stem-cell technologies to make a powerful tool for diabetes research and beta-cell transplantation By Mary Todd Bergman By combining two powerful technologies, scientists are taking diabetes research to a...

Harvard-led research boosts the yield of insulin-producing cells for diabetes therapy By Jessica Lau Summary Harvard University researchers used single-cell sequencing to identify a protein expressed uniquely by insulin-producing beta cells created from...

Sana Biotechnology licenses innovative immune-silent stem cell technology developed though Harvard’s Blavatnik Biomedical Accelerator Protecting transplanted cells from immune attack is a serious challenge. As with any organ transplant, cell lines derived...

Chad Cowan is on a quest for the universal donor, which would make cell therapy available to populations – not just individuals. Harvard scientist Chad Cowan aims to make off-the-shelf cellular products, and democratize access to new medicines. His lab is...

Applications for 2018 Joslin Pilot & Feasibility grants now open to all Harvard/Affiliates. The goal of the Pilot and Feasibility Study Program is to encourage research on diabetes and its complications by two target groups: young researchers in these...

This scanning electron microscope image shows the T cell-trapping biomaterial up-close with cavities and ducts allowing the entry, as well as movement and binding of autoimmune T cells in its interior. Photo courtesy of James Weaver. An approach that...

Adapted from a Joslin Diabetes Center press release Diabetes researchers have puzzled for decades about why insulin-producing beta cells in one pancreatic islet often look and behave quite differently than their counterparts in the same islet or in nearby...

In a flask of clear, pale yellow liquid, 300-400 million beta cells, the insulin-producing cells attacked or defective in diabetics, swirl in a cocktail of cell food and Stage 6 medium. Ten years ago, researchers were still working on protocols to turn...