Blood Diseases Program

New technique raises possibility of making all types of blood cells to treat disease By Nancy Fliesler, Boston Children's Hospital Communications Harvard Stem Cell Institute researchers at Boston Children’s Hospital have, for the first time, generated...

Bone marrow from a young boy diagnosed with Diamond-Blackfan anemia (DBA) shows a reduced number of erythroid precursor cells. In this case, an unusual gene mutation in the hormone EPO was identified and found to cause the anemia. Photo courtesy of Ekrem...

Red blood cells were successfully made via induced pluripotent stem cells from a Diamond-Blackfan anemia patient. Image: Daley lab, Boston Children’s For first time, iPS cells flag potential drug for blood disease By Nancy Fliesler Harvard Stem Cell...

Immature (undifferentiated) cells are on the left panel and cells that have differentiated in response to treatment with brequinar are on the right panel. Photo courtesy of Scadden Lab. Simple compound could provide first new therapy for AML in four...

HSCI codirector David Scadden has been named a Fellow of the American Association for the Advancement of Science (AAAS). This year 391 members have been awarded this honor by AAAS because of their scientifically or socially distinguished efforts to...

Photo courtesy of Vionnie Yu, Scadden Lab. Color-labeling helps Harvard researchers track the development and behavior of individual cells By Hannah Robbins Harvard Stem Cell Institute (HSCI) researchers have used a colorful, cell-labeling technique to...

Startup Magenta Therapeutics licences technologies from Harvard, MGH, and Boston Children's that could transform treatment of blood diseases and immune disorders Harvard University has completed a license agreement with Magenta Therapeutics, a new startup...

HSCI scientists use antibodies, rather than the standard toxic chemicals and radiation, to prepare for bone marrow transplants By Hannah L. Robbins Harvard Stem Cell Institute (HSCI) scientists have taken the first steps toward developing a treatment that...

Researchers from Dana-Farber/Boston Children's Cancer and Blood Disorders Center have found that changes to a small stretch of DNA may circumvent the genetic defect behind sickle cell disease. Photo courtesy of EM Unit, UCL Medical School, Royal Free...

Compounds boost stem cell engraftment; could allow more matches for patients with cancer and blood diseases By Nancy Fliesler Boston Children’s Hospital Using large-scale zebrafish drug-screening models, Harvard Stem Cell Institute (HSCI) researchers at...