Massachusetts General Hospital

The Chetty lab is interested in understanding the mechanisms underlying neurodevelopmental and psychiatric disorders, such as autism spectrum disorder and schizophrenia.

Studying these disorders and finding effective therapies has been challenging...

Osteoporosis is a major public health problem in our aging population. Fragility fractures cause pain, lack of functional independence, and increased mortality. New therapeutic strategies are sorely needed to boost bone formation and cure osteoporosis. In...

The Dou laboratory seeks to understand the biology of aging and to develop new strategies for intervening in age-related diseases. 

The Dou lab investigates the intersection of aging and cancer, with a particular emphasis on nuclear events. Their...

Mario Suva's research is focused on the biology of brain tumors, in particular diffuse high-grade gliomas in adults and children.

We dissect how cellular heterogeneity and plasticity contribute to tumor properties. We study primary human samples at...

The Wainger Lab focuses on how abnormalities of motor and sensory neuron physiology contribute to diseases such as ALS and chronic pain.

The aim of the Wainger Laboratory is to ask clinically relevant research questions that could lead to rapid...

The incidence and complexity of mental illnesses and cognitive impairments associated with aging and Alzheimer’s disease underscores the need to develop novel treatments. Our mission is to generate fundamental insights into the role of hippocampal...

The Rajagopal lab focuses on organ regeneration and the application of developmental biology to human disease. They utilize the lung as a model system, in part due to the abundance of respiratory diseases of unknown causes and without cures.

The lung is...

The Langenau lab investigates how it is that tumors can be remade following conventional chemotherapeutic intervention, using zebrafish as a model.

Our research focuses on using the zebrafish to better understand human cancer and to develop novel...

My laboratory studies how atherosclerosis—narrowing and hardening of the arteries—occurs. Atherosclerosis leads to abnormalities in blood vessels and eventually affects the flow of blood. When atherosclerosis occurs in the arteries that supply blood to...

Our laboratory is interested in the transcriptional regulation of normal blood cell development and leukemia. All blood cells arise from a small population of hematopoietic stem cells (HSCs) that have the capacity to, both, self-renew and mature stepwise...