Massachusetts General Hospital

The Hochedlinger lab investigates the role stem cells play in normal development and disease.

Stem cells have the dual potential to self-renew and give rise to mature cells. They play key roles in development, during tissue homeostasis and following...

The Gusella lab investigates nervous system disease using molecular genetic strategies, beginning with human patients and proceeding through in vitro and modeling studies, with the ultimate goal of improving diagnosis, prevention, management and

The Galloway lab aims to apply new discoveries to developing regenerative biology solutions that can better heal and repair tendon and ligament injuries.

Injuries to tendons and ligaments result in a slow, imperfect regenerative response. In most cases...

The Pediatric Surgical Research Laboratories focus on Developmental Biology, some areas of which hold promise for clinical application to benefit both pediatric and adult patients.

Patricia Donahoe, M.D., David MacLaughlin, Ph.D., and Jose Teixeira, Ph.D...

The laboratory focuses on the biology and structure of integrins, a major class of cell adhesion receptors that play vital roles in normal physiology but also in disease, and on using the derived information to design and test novel anti-integrin...

The Scadden laboratory focuses on blood, in particular the regulation of the hematopoietic stem cell by its microenvironment or niche. Their goal is to make bone marrow transplants safer and easier for both patients and donors.

Using a combination of...