Cancer

Scott Armstrong studies the mechanisms of cancer development, focusing on leukemia. One major interest of this lab is the relationship between leukemia, normal hematopoietic stem cells and the various hematopoietic cells of origin of leukemia.

The...

Alessandra Biffi is actively involved in gene therapy trials for genetic diseases of childhood. Her research focuses on enhancing the efficacy of HSC-based therapeutic approaches for LSDs with severe nervous system involvement.

Hematopoietic stem cell...

Dr. Vijay Sankaran’s laboratory studies how human genetic variation impacts human blood cell production or hematopoiesis in health and disease.

The Sankaran Laboratory utilizes human genetics to refine our understanding of hematopoiesis and how this...

Markus Frank's laboratory defined a novel function for ABCB5 in cancer stem cell maintenance and tumor growth, and investigates the therapeutic efficacy of ABCB5 targeting in melanoma and additional ABCB5-expressing human malignancies.

Research in the...

The Murphy lab studies scarless healing during fetal development and “stem cell burnout” during aging, with the goal of coaxing skin stem cells into healing wounds by regenerating tissue instead of forming a scar.

The Murphy Laboratory focuses on...

Yingzi Yang's research has bridged discoveries of fundamental mechanisms with the characterization and treatment of diseases including severe birth defects, osteoporosis, osteoarthritis and heterotopic bone formation.

The Yang lab uses molecular...

The Slack lab seeks to translate their discoveries of the roles of microRNAs into potential cures and biomarkers for cancer and aging.

My lab has pioneered various aspects of the microRNA field and continues to make important contributions to this aspect...

The Bauer laboratory studies the genetic determinants of blood cell ontogeny and disease.

The lab uses molecular genetic, biochemical, and genome editing methodologies to perturb and observe blood cells. They are particularly interested in the role of...

Yick Fong's research aims to elucidate the full repertoire of transcription factors operating in stem cells, so that the full potential of stem cells in tissue regeneration and replacement therapy can be realized.

We study key transcriptional and gene...

The Zon laboratory aims to dissect how assaults to the hematopoietic system cause severe diseases such as leukemias, lymphomas, and anemias. They investigate hematopoietic development and disease using chemical screens, genetic screens, and analysis of