Dana-Farber Cancer Institute

Jose Cancelas is a MD, PhD, hematologist with a broad background in transfusion medicine, cell therapies, hematology, and stem cell biology. He is the executive director of the Connell and O’Reilly Cell Manipulations Core Facility at Dana Farber Cancer...

We are interested in unlocking new paradigms of normal blood development with the long-term aim of building better models of childhood blood diseases.  The process of blood formation changes over a lifetime: the blood stem cells formed in the embryo...

Zuzana Totova's laboratory is group of physicians and scientists who are passionate about tackling important questions in cancer biology, and aim to improve outcomes for cancer patients. Their research focuses on genetics and epigenetics of blood cancers

The Ebert lab focuses on the molecular basis and treatment of hematologic malignancies, with a particular focus on myelodysplastic syndromes (MDS).

In large-scale genetic analyses of patient samples, the lab has identified somatic mutations that predict...

Scott Armstrong studies the mechanisms of cancer development, focusing on leukemia. One major interest of this lab is the relationship between leukemia, normal hematopoietic stem cells and the various hematopoietic cells of origin of leukemia.

The...

Alessandra Biffi is actively involved in gene therapy trials for genetic diseases of childhood. Her research focuses on enhancing the efficacy of HSC-based therapeutic approaches for LSDs with severe nervous system involvement.

Hematopoietic stem cell...

Dr. Vijay Sankaran’s laboratory studies how human genetic variation impacts human blood cell production or hematopoiesis in health and disease.

The Sankaran Laboratory utilizes human genetics to refine our understanding of hematopoiesis and how this...

The Yuan lab develops systems biology approaches to study the cellular mechanisms for tissue development and human diseases.

We develop novel computational methods to analyze and integrate genome-scale datasets, and partner with experimental biologists...

The He laboratory aims to develop functional restoration strategies after CNS injury and diseases such as spinal cord injury (SCI), glaucoma, and traumatic brain injury (TBI).  

A major cause of permanent functional deficits after CNS injuries and diseases...

The Bauer laboratory studies the genetic determinants of blood cell ontogeny and disease.

The lab uses molecular genetic, biochemical, and genome editing methodologies to perturb and observe blood cells. They are particularly interested in the role of...