The Gusella lab investigates nervous system disease using molecular genetic strategies, beginning with human patients and proceeding through in vitro and modeling studies, with the ultimate goal of improving diagnosis, prevention, management and
Dr. Ole Isacson and the Neuroregeneration Research Institute (NRI) at McLean Hospital are at the forefront of research into regenerative medicine for brain disorders.
The Neuroregeneration Laboratories and Institute have an impact on several...
The Macklis lab seeks to apply developmental controls toward brain and spinal cord regeneration and directed differentiation for therapeutic and mechanistic screening.
Research in the Macklis lab is directed toward both
Collaborators from HSCI, Massachusetts General Hospital (MGH), Beth Israel Deaconess Medical Center (BIDMC), and the Harvard Medical School have shown that neuronal transplants can repair brain circuitry and substantially normalize function in mice with a...
While much of the public discussion and debate concerning stem cell research has focused on the possibility of developing stem cell therapies for a myriad of chronic, often fatal diseases, scientists have been equally excited by the potential that stem...
In the right-hand picture, an SMA mouse treated with guanabenz, a compound known to reduce cellular stress, shows healthy junctions between muscle cells (red) and motor nerve fibers (green). In contrast, the untreated SMA mouse (left) has lost its nerve...
The pace of discovery in stem cell research went into overdrive recently as scientists unveiled new methods for returning mature adult cells (such as skin cells) to an immature, embryonic-like state. The implications for both scientists and patients are...
Guest speaker: Hilary Goldberg, MD Medical Director, Lung and Transplant Program Brigham and Women's Hospital Please RSVP to Ramya Sampath at rsampath@partners.org *Directions to the Conference Room: One Brigham Circle is located at the intersection of...
Whether studying the fundamental properties of stem cells or screening disease-specific stem cells to search for potential therapeutics, all HSCI researchers share a common goal—to find cures for many pernicious diseases, both common and rare, as quickly...
December 2017 12/18/17 A Wall Street Journal video highlights Harald Ott’s work on organ regeneration. 12/16/17 In an article by The Guardian , James Gusella comments on the potential of gene therapy to treat Huntington’s disease. 12/7/17 An article by...
BWH Regenerative Medicine Center-Leaders in Regenerative Medicine Seminar Series Guest speaker: David T. Scadden, MD Gerald & Darlene Jordan Professor of Medicine, Harvard University Co-chair and Professor, Dept. of Stem Cell & Regenerative Biology...
Lecturer: John Ioannidis, DSc, MD C.F. Rehnborg Professor in Disease Prevention and Professor of Health Research and Policy Stanford School of Medicine During the 2014-15 academic year, the Harvard Catalyst Biostatistics Program will present a series of...