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Biohybrid fish made from human cardiac cells swims like the heart beats

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Bioengineered device offers insights into artificial muscular pumps, a step toward building an artificial heart Harvard University researchers, in collaboration with colleagues from Emory University, have developed the first fully autonomous biohybrid...

Harvard University licenses kidney engineering technology to Trestle Biotherapeutics

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Combination of 3D bioprinting and stem cell-based tissue engineering could enable new approaches to treating chronic kidney disease A newly launched startup is building on innovations developed over several years at the Wyss Institute for Biologically...

Harvard University licenses technology to Alkem, aiming to treat ischemic injury and vascular diseases

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Novel delivery system for tissue-regenerative molecules enables local, sustained release for greater efficacy Alkem Laboratories Limited (Alkem) has signed a license agreement with Harvard University’s Office of Technology Development to develop and...

Cyborg brain organoids offer insight into early brain development

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Since their development more than a decade ago, brain organoids — brain-like structures grown in petri dishes from human stem cells — have helped scientists better understand a range of neurological disorders, including schizophrenia, epilepsy, and autism...

Reviving cells after a heart attack

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HSCI researchers show the healing mechanisms of extracellular vesicles using a heart-on-a-chip Extracellular vesicles (EVs) — nanometer-sized packages that travel between cells to deliver cues and cargo — are promising tools for the next generation of...

A solid vaccine for liquid tumors

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Biomaterial-based vaccine protects against acute myeloid leukemia in mice Acute myeloid leukemia (AML), a blood cancer that originates in the bone marrow has been treated with chemotherapy for over 40 years. While the treatment does often cause the cancer...

Immuno-engineering to Improve Immunotherapy (i3) Center launches

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Cancer immunologists and biological engineers at Harvard unite to fight therapy-resistant cancers A new NIH-funded Immuno-Engineering to Improve Immunotherapy (i3) Center at Harvard University sets out to create new anti-cancer immunotherapies using...

Developing bioengineered protective materials for COVID-19

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Face masks and hand sanitizers are essential tools to prevent the spread of COVID-19. But what if these essentials could be supercharged? HSCI researchers are developing bioengineered protective materials, including a nasal spray that could keep the virus...

Helping the clinical community

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Researchers in the Jennifer Lewis lab have developed low-cost, plastic and foam-based face shields that can be quickly mass produced. After working with health care professionals on the best design, the researchers have to date delivered almost 1,000 face...

Restoring hearing loss through regenerative medicine

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A one-time treatment using small molecules to target progenitor cells, pioneered in the lab of a Harvard Stem Cell Institute researcher, may potentially restore hearing lost from some of the most common causes By Alice McCarthy Often regarded as a quasi...

Stem cell performance enhanced with steroids

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Harvard stem cell scientists at Brigham and Women’s Hospital have pioneered a method using steroids to make mighty stem cells, increasing their usefulness for potential cell therapies. Unlike sports, where performance-enhancing drugs are banned, in the...

Stem cells engineered to become targeted drug factories

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A group of Brigham and Women’s Hospital, and Harvard Stem Cell Institute researchers, and collaborators at MIT and Massachusetts General Hospital have found a way to use stem cells as drug delivery vehicles. The researchers inserted modified strands of...