Parkinson's Disease

New discoveries about the role of alpha-synuclein, a well-known protein marker of Parkinson’s, may provide insights for treatment for the disease One of the hallmarks of Parkinson’s disease (PD) is the accumulation in the brain of a protein known as alpha...

HSCI Principal Faculty member Vikram Khurana has received three awards to advance his innovative research on Parkinson’s disease, a neurodegenerative disorder that impacts millions of patients around the world. Khurana is a winner of the “ Ken Griffin...

Harvard Stem Cell Institute researchers at the Ann Romney Center for Neurologic Diseases at Brigham and Women’s Hospital have shed new light on the underlying mechanisms of Parkinson’s disease, a progressive neurological disorder that could leave the...

Ole Isacson and colleagues reported that dopamine-producing neurons (pictured) derived from the skin cells of primates survived for more than two years after implantation into one of the animals. Isacson noted that the animal was “able to move as fast...

Finding may lead to transplanting dopamine neurons taken from stem cells grown in labs Harvard Stem Cell Institute researchers at McLean Hospital have found that fetal dopamine cells transplanted into the brains of patients with Parkinson’s disease were...

A nationwide consortium of scientists at 20 institutions, led by a principal faculty member at the Harvard Stem Cell Institute (HSCI), has used stem cells to take a major step toward developing personalized medicine to treat Parkinson’s disease. In part...

HSCI scientists have developed new ways to identify, grow, sort, and transplant the dopamine-producing cells that are lost in Parkinson’s disease. Additionally, they have learned how to identify and remove unwanted cells prior to transplantation, such as...