Musculoskeletal Disease

This post originally appeared on the Mass General Research Institute blog Autumn means the return of fall sports such as soccer and football. Unfortunately, it can also lead to a new wave of sports-related injuries such as tendon tears. Last month, New...

Study finds that fatty acids influence skeletal stem cell development When a bone fracture occurs, the stem cells that repair the injury either form new bone or new cartilage. A new study in the journal Nature has identified how this decision happens...

HSCI research receives support from Sarepta to advance in-vivo genome editing toward prospective therapy HSCI researchers led by Amy Wagers, Ph.D. are embarking on a major study of Duchenne muscular dystrophy (DMD). The project aims to use in vivo genome...

Adapted from a Boston Children's Hospital press release. Two golden retrievers that had the genetic mutation for Duchenne muscular dystrophy (DMD), yet remained healthy, have offered up yet another lead for treating this muscle-wasting disorder. For...

Tongue-on-a-chip provides insight into genetic diseases By Leah Burrows, SEAS Science and Technology Communications Officer Muscular dystrophy is a group of rare genetic diseases that cause progressive muscle weakness and deterioration. For decades...

Current and former HIP interns launch research projects on the same rocket by Hannah L. Robbins Mosquitos buzzed in the warm, night air at Cape Canaveral, Florida. Half past midnight on July 18, and still the spectators could not detect activity on the...

Lee Rubin, PhD, and Amy Wagers, PhD, (below) of the Harvard Stem Cell Institute provide more evidence that a protein known as GDF11 reverses signs of aging in mice. (Credit: B.D. Colen/Harvard University) Harvard stem cell researchers advance...

Harvard stem cell scientists have found that cells known primarily for tempering immune response also exist in injured muscle tissue, an unexpected role for regulatory T cells. Regulatory T cells, or Tregs for short, accumulate in the skeletal muscles of...

Harvard Stem Cell Scientists have discovered that the same chemicals that stimulate muscle development in zebrafish can also be used to differentiate human stem cells into muscle cells in the laboratory, an historically challenging task that, now overcome...