Cancer

Discovery of new mechanism could have wide implications for other cancers By Alice McCarthy Researchers from Harvard’s Stem Cell and Regenerative Biology (HSCRB)’s Zon lab have discovered a new mechanism that influences melanoma development, a finding...

Kara McKinley, PhD, principal faculty at HSCI, has been named one of the 2022 class of Packard Fellows for Science and Engineering. McKinley and 19 other innovative early-career scientists and engineers will each receive $875,000 over five years to pursue...

Dr. McKinley will receive $1.5 million over five years to continue her work in uterine regeneration, focused on establishing an animal model of menstruation. By Alice McCarthy The NIH Director’s New Innovator Award recognizes career excellence among early...

Fernando Camargo recognized for pioneering scientific contributions and outstanding leadership Fernando Camargo, Ph.D., has been named as the inaugural Regenerative Biology Endowed Chair by the Boston Children’s Hospital (BCH) Department of Pediatrics, in...

AWARD AMOUNT Up to $100,000 for entire project period Project period not to exceed 2 years POSTED DATE Wednesday, February 2, 2022 DEADLINE FOR APPLICATION Friday, March 4, 2022 ANTICIPATED AWARD DATE April 1, 2022 The Harvard Stem Cell Institute (HSCI)...

For most cells within the body, identity is non-negotiable: a bladder cell cannot impersonate a blood cell, and a liver cell remains a liver cell. One of the rare exceptions has been thought to be a condition known as Barrett’s esophagus, in which the...

Bone metastases are devastating developments of cancers that originate in other organs. In the case of metastatic prostate cancer, bone metastases represent an incurable, painful, and often deadly development, killing more than 30,000 American men every...

HSCI researchers identify mechanism with therapeutic potential for anemia Each tissue in the body has different requirements for metabolism, or how it uses energy to function — for example, a muscle needs different molecules to fuel a contraction compared...

Harvard Stem Cell Institute (HSCI) researchers have engineered stem cells that can deliver a tumor-suppressing and killing molecule to the brain. They tested the therapy in three new mouse models of breast cancer that metastasizes to the brain, and found...

HSCI researchers create ON-OFF switches to better control CAR T cell activity HSCI scientists have created molecular ON-OFF switches to regulate the activity of CAR T cells, a potent form of cell-based immunotherapy that has shown dramatic success in...