Bioengineering

Brigham and Women's press release - 10-Oct-2017 Medical implants can save lives by correcting structural defects in the heart and other organs. But until now, the use of medical implants in children has been complicated by the fact that fixed-size...

New approach offers promise for long-term efficacy by Kelly Lawman, Beth Israel Deaconess Medical Center Blood-contacting implantable medical devices, such as stents, heart valves, ventricular assist devices, and extracorporeal support systems, as well as...

Stem cell-derived, glucose-stimulated, insulin-producing cells (SC-β) are protected inside capsules engineered to be invisible to the host immune system. Photo courtesy of Omid Veiseh and Andrew Bader/Anderson/Langer Laboratory, Koch Institute at MIT...

The Anc80 virus delivered genes to the mouse retina that fluoresce green when expressed. Pictured here, the delivered genes are active in the retina's color-detecting cells. Photo credit: Livia Carvalho An ancient virus may bring gene therapy options to...

Proof-of-concept study highlights new therapeutic use of engineered human stem cells Harvard Stem Cell Institute scientists at Massachusetts General Hospital have devised a new way to use stem cells in the fight against brain cancer. A team led by...

Researchers experiment with single shot that slows rejection A drug-secreting gel that holds back the immune system—developed to help treat diseases such as brain cancer, ulcerative colitis, and arthritis—has now been shown to slow hand transplant...

Stem cells loaded with cancer-killing herpes virus attack a brain tumor cell. Tumor cells in green. oHSV-loaded stem cells in red. oHSV-infected tumor cells in yellow. (Credit: Khalid Shah/MGH) Harvard Stem Cell Institute (HSCI) scientists at...

Cross-Harvard collaboration explores new possibilities for personalized medicine Harvard scientists have merged stem cell and ‘organ-on-a-chip’ technologies to grow, for the first time, functioning human heart tissue carrying an inherited cardiovascular...

Harvard stem cell scientists at Brigham and Women’s Hospital have pioneered a method using steroids to make mighty stem cells, increasing their usefulness for potential cell therapies. Unlike sports, where performance-enhancing drugs are banned, in the...

Harvard stem cells scientists at Brigham and Women’s Hospital and MIT can now engineer cells that are more easily controlled following transplantation, potentially making cell therapies, hundreds of which are currently in clinical trials across the United...