Aging

Scientists develop a gene therapy to reverse age-related vision loss and glaucoma damage in mice Harvard Stem Cell Institute (HSCI) scientists are part of a team that has successfully restored vision in mice by turning back the clock in aged eye cells in...

Researchers awarded funding by the Simons Collaboration on Plasticity and the Aging Brain Two HSCI scientists have joined the Simons Collaboration on Plasticity and the Aging Brain. Funded by the Simons Foundation, the effort has pledged $42 million over...

HSCI researchers have identified potential drugs to treat telomere diseases such as dyskeratosis congenita (DC), in which cells age prematurely. The researchers tested over 100,000 compounds on patient stem cells, and identified several drugs that...

HSCI researchers take a single-cell dive into how aging affects gene expression in the mouse brain By Jessica Lau HSCI researchers have created a highly detailed map of how the mouse brain changes with age. Using single-cell sequencing, the scientists...

George Murphy wants to use stem cells to replace scarring with regenerative healing. George Murphy’s goal is to coax skin stem cells into healing wounds by regenerating tissue instead of forming a scar. To figure out how to do it, he is studying scarless...

Zebrafish help solve an evolutionary puzzle, and may help make blood stem cell transplants safer This still image, from an HHMI video about the work of the Zon laboratory, shows how blood stem cells are protected from ultraviolet radiation in zebrafish...

Lee Rubin, PhD, and Amy Wagers, PhD, (below) of the Harvard Stem Cell Institute provide more evidence that a protein known as GDF11 reverses signs of aging in mice. (Credit: B.D. Colen/Harvard University) Harvard stem cell researchers advance...

Harvard stem cell researchers and scientists at the University of Cambridge in the United Kingdom have found that the age-related degeneration in conditions such as multiple sclerosis (MS) may be reversible. The researchers, co-led by Associate Professor...

Two Harvard Stem Cell Institute (HSCI) researchers — a stem cell biologist and a practicing cardiologist at Brigham and Women’s Hospital — have identified a protein in the blood of mice and humans that may prove to be the first effective treatment for the...