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William Pu

Content tagged with William Pu

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Gene therapy for Barth syndrome

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HSCI researchers reverse heart failure in mice HSCI researchers have successfully tested a gene therapy in mice for Barth syndrome, a rare disease that can cause life-threatening heart failure. Published in the journal Circulation Research, the study...

Tissue models and a gene therapy for a deadly heart arrhythmia

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Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a leading cause of sudden death from cardiac arrest in children and young adults. Marked by racing, irregular heartbeats, the inherited arrhythmia is typically silent until a child suddenly...

Heart research gets a better 3D model

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HSCI bioengineer and cardiologist collaborate to design a radically improved model of the heart By Jessica Lau Researchers use heart cells in the laboratory to study heart disease and test potential new therapies. Many of the heart disease models they use...

Patient stem cells used to make ‘heart disease-on-a-chip’

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Cross-Harvard collaboration explores new possibilities for personalized medicine Harvard scientists have merged stem cell and ‘organ-on-a-chip’ technologies to grow, for the first time, functioning human heart tissue carrying an inherited cardiovascular...