Leonard Zon

Discovery of new mechanism could have wide implications for other cancers By Alice McCarthy Researchers from Harvard’s Stem Cell and Regenerative Biology (HSCRB)’s Zon lab have discovered a new mechanism that influences melanoma development, a finding...

HSCI researchers identify mechanism with therapeutic potential for anemia Each tissue in the body has different requirements for metabolism, or how it uses energy to function — for example, a muscle needs different molecules to fuel a contraction compared...

HSCI scientists find that signaling defects can influence red blood cell traits The field of genetics has made huge strides over the past couple of decades, from the first sequencing of the human genome to a growing understanding of the machinery that...

Zebrafish models could help develop precision cancer therapies HSCI scientist Leonard Zon, M.D. uses zebrafish as a model to study different cancers. Now, he has used this approach to reveal how mutations in a gene called SPRED1 are involved in mucosal...

HSCI, a network of the nation’s top stem cell and regenerative medicine researchers, gathers to exchange ideas and forge new collaborations to advance biomedical research. Summary 2018 gathering of stem cell scientists provided rich ground for knowledge...

Zebrafish help solve an evolutionary puzzle, and may help make blood stem cell transplants safer This still image, from an HHMI video about the work of the Zon laboratory, shows how blood stem cells are protected from ultraviolet radiation in zebrafish...

Red blood cells were successfully made via induced pluripotent stem cells from a Diamond-Blackfan anemia patient. Image: Daley lab, Boston Children’s For first time, iPS cells flag potential drug for blood disease By Nancy Fliesler Harvard Stem Cell...

Photo courtesy of Vionnie Yu, Scadden Lab. Color-labeling helps Harvard researchers track the development and behavior of individual cells By Hannah Robbins Harvard Stem Cell Institute (HSCI) researchers have used a colorful, cell-labeling technique to...

Two HSCI Principal Faculty members, Leonard Zon, MD, and Fernando Camargo, PhD, have received awards for their outstanding contribution to the field of stem cell science from the International Society for Stem Cell Research (ISSCR), a world-renowned...

First demonstration of a cancer arising from a single cell by Nancy Fliesler, Boston Children's Hospital Harvard Stem Cell Institute researchers at Boston Children’s Hospital have, for the first time, visualized the origins of cancer from the first...