Khalid Shah

Results suggest a pathway to testing in human clinical trials In a new study, researchers have discovered a method for using engineered donor stem cells to successfully treat glioblastoma in mice. The study revealed the presence of special “death...

Harvard Stem Cell Institute (HSCI) researchers have engineered stem cells that can deliver a tumor-suppressing and killing molecule to the brain. They tested the therapy in three new mouse models of breast cancer that metastasizes to the brain, and found...

Engineered cancer cells can deliver therapeutic molecules to tumors in mice By Jessica Lau Cancer cells have a self-homing ability: they can move around the body to locate tumors. This usually helps the cancer to spread, but Harvard Stem Cell Institute...

In spring, 2017, Khalid Shah and Tracy Young-Pearse were settled in their new research home in Brigham and Women’s ‘Building for Transformative Medicine’ on Fenwood Road. Like good neighbors, they were very eager to get to know their HSCI colleagues in...

Stem cells loaded with oncolytic viruses target skin cancer metastases in the brain Investigators from Brigham and Women’s Hospital (BWH) and the Harvard Stem Cell Institute have a potential solution for how to kill tumor cells that have metastasized to...

Tagged therapeutic stem cells (green) targeting breast cancer metastases (red) in the brain of a mouse model. Animal model of breast-to-brain cancer spread allows testing of therapeutic-cell approach Sue McGreevey, Massachusetts General Hospital Public...

Proof-of-concept study highlights new therapeutic use of engineered human stem cells Harvard Stem Cell Institute scientists at Massachusetts General Hospital have devised a new way to use stem cells in the fight against brain cancer. A team led by...

Stem cells loaded with cancer-killing herpes virus attack a brain tumor cell. Tumor cells in green. oHSV-loaded stem cells in red. oHSV-infected tumor cells in yellow. (Credit: Khalid Shah/MGH) Harvard Stem Cell Institute (HSCI) scientists at...