Harvard Department of Stem Cell and Regenerative Biology

Our research aims to understand the role of long intergenic non-coding RNAs (lincRNAs) in establishing the distinct epigenetic states of adult and embryonic cells and their misregulation in diseases such as cancer. To further explore how lincRNAs may...

Sharad Ramanathan studies how multi-potent cells make developmental decisions and how the nervous system makes behavioral decisions.

Our laboratory focusses studying how multi-potent cells make developmental decisions and how the nervous system makes...

The Macklis lab seeks to apply developmental controls toward brain and spinal cord regeneration and directed differentiation for therapeutic and mechanistic screening.

Research in the Macklis lab is directed toward both

1. understanding molecular controls...

Richard T. Lee's laboratory seeks to understand heart failure and metabolic diseases that accompany human aging, and to translate that understanding into therapies, including stem cell transplantation strategies and new biological agents.

The Lee...

Steven Hyman directs the Stanley Center for Psychiatric Research of the Broad Institute of Harvard and MIT.

The Stanley Center focuses on psychiatric disorders, neurodevelopmental conditions, and neurodegenerative disorders including schizophrenia...

The Hochedlinger lab investigates the role stem cells play in normal development and disease.

Stem cells have the dual potential to self-renew and give rise to mature cells. They play key roles in development, during tissue homeostasis and following...

The Camargo laboratory focuses on the study of adult stem cell biology, organ size regulation, and cancer.

Despite fantastic progress in developmental biology research over the past decade, one aspect of development and tissue homeostasis for which very...

The Arlotta lab research program explores the interface between development and engineering of the neocortex, to gain fundamental understanding of both the principles that govern normal cortical development and of previously-inaccessible mechanisms of

The Scadden laboratory focuses on blood, in particular the regulation of the hematopoietic stem cell by its microenvironment or niche. Their goal is to make bone marrow transplants safer and easier for both patients and donors.

Using a combination of...