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Harald Ott and team from MGH creates functional, stem cell-derived small bowel segments

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Press release of the Massachusetts General Hospital Using human induced pluripotent stem cells (iPSCs), a Massachusetts General Hospital (MGH) research team has bioengineered functional small intestine segments that, when implanted into rats, were capable...

Surgical Implant that Grows with a Child

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Brigham and Women's Hospital Press Release, 10-Oct-2017 Medical implants can save lives by correcting structural defects in the heart and other organs. But until now, the use of medical implants in children has been complicated by the fact that fixed-size...

HSCI Faculty "extraordinary" innovation recognized by the NIH

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HSCI Faculty ‘extraordinary’ innovation recognized by the NIH HSCI Principal Faculty members Jeffrey Macklis, Alex Schier and Brian Wainger were recently recognized ‘for exceptional creativity’ by the NIH’s High-Risk, High-Reward Research program. Jeff...

The Organ Generation is featured HUBweek event

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Organoids - A New Window into Disease, Development and Discovery

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Scientists have found ways of culturing organ-specific tissue from stem cells that could change the way diseases are studied and treated. by Javier Barbuzano for HSCI Imagine the possibility of creating individualized, complex collections of cells that...

Making Mature Nephrons

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Using normal kidney development as a roadmap, HSCI Executive Committee member Joseph Bonventre and a team of researchers developed an efficient method to make human kidney precursor cells . The precursor cells self-assembled into organoids, which could be...

Repairing DMD Genes in Mice

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A team of researchers, led by HSCI Executive Committee member Amy Wagers, was able to restore the production of functional dystrophin protein in mouse models of Duchenne muscular dystrophy. Using CRISPR-Cas9 to excise faulty exons, the team was able to...

MSC Colloquium

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“Mesenchymal stem cells are like sushi,” Jacques Galipeau, MD, told an audience of the world’s premiere MSC researchers, clinicians, and bioengineers in his keynote address at Harvard Stem Cell Institute’s (HSCI) Mesenchymal Stem Cell Colloquium. “Fresh...