Our goal is to develop significant new treatments for diabetes. We aim to eliminate the present practice of regular blood checks and insulin injections, replacing them with insulin-producing cell transplants, specifically pancreatic beta cells that...
Jose Cancelas is a MD, PhD, hematologist with a broad background in transfusion medicine, cell therapies, hematology, and stem cell biology. He is the executive director of the Connell and O’Reilly Cell Manipulations Core Facility at Dana Farber Cancer...
Dr. Sunil Chauhan is an immunologist and translational scientist whose research focuses on transplantation immunology, regenerative immunology, and immune regulation in tissue injury. His work has advanced the understanding of immune mechanisms governing...
The Simoes-Costa lab focuses on decoding the molecular programs that orchestrate cell differentiation in the vertebrate embryo.
We employ functional genomics to characterize the gene regulatory circuits that control cell state transitions during...
Studying these disorders and finding effective therapies has been challenging...
We are interested in unlocking new paradigms of normal blood development with the long-term aim of building better models of childhood blood diseases. The process of blood formation changes over a lifetime: the blood stem cells formed in the embryo...
The Van Galen Laboratory studies normal and malignant hematopoiesis, with a focus on hematopoietic stem cell aging and the development of acute myeloid leukemia. Our projects span age-associated inflammatory pathways, targeted therapies for leukemia, and...
The Flynn lab is focused on the exploration and discovery of how biopolymers like RNA and glycans work together to control cellular processes in the context of human disease.
Glycans regulate a myriad of essential cellular functions, especially in the...
The McKinley lab studies regeneration in the uterus and the biology of menstruation.
The McKinley laboratory studies the uterus to advance reproductive health and regenerative medicine. The human uterine lining (endometrium) undergoes dramatic tissue...
The principal activities of the Lewis Group involve 3D printing of soft functional materials for use in printed electronics, optical materials, light-weight structures, and microvascular architectures for cell culture and tissue engineering.
Jennifer has...