Osteoporosis is a major public health problem in our aging population. Fragility fractures cause pain, lack of functional independence, and increased mortality. New therapeutic strategies are sorely needed to boost bone formation and cure osteoporosis. In...
The Franklin laboratory is focused on understanding fundamental biological principles at the intersection of immunology and regenerative biology.
Currently, we study the role of immune cells in tissue building and rebuilding in the context of injury...
Dr. Fei Chen is an assistant professor at the Harvard Department of Stem Cell and Regenerative Biology, and a Core Faculty member at the Broad Institute.
During his doctoral research, Chen co-invented expansion microscopy, a breakthrough technique...
Intriguingly, some mammalian digit tips (including mouse and human children) can regenerate following amputation, demonstrating that mammals...
We are developing a training environment where we apply emerging techniques...
The Dou lab investigates the intersection of aging and cancer, with a particular emphasis on nuclear events. Their...
To do this, the Buenrostro lab develops new technologies utilizing molecular biology, microscopy and...
In large-scale genetic analyses of patient samples, the lab has identified somatic mutations that predict...
We dissect how cellular heterogeneity and plasticity contribute to tumor properties. We study primary human samples at...