#  Pluripotency and Reprogramming Symposium 

 



####  calendar\_today Date and Time 

 **April 17, 2015** 

 08:30AM - 07:30PM EDT 

####  pin\_drop Location 

 **Broad Institute, Auditorium, 415 Main Street, Cambridge, MA**  



 

 



 

Human ​pluripotent ​stem ​cells ​possess ​the ​ability ​to ​self ​renew ​in ​vitro ​while ​maintaining ​a ​developmental ​plasticity ​that ​is ​ similar ​to ​that ​exhibited ​by ​progenitor ​cells ​of ​the ​very ​ early ​embryo. ​As ​a ​result, ​pluripotent ​stem ​cells ​may ​provide ​ an ​inexhaustible ​supply ​of ​any ​differentiated ​cell ​type ​for ​ both ​in ​vitro ​studies ​of ​disease ​and ​regenerative ​medicine.   
   
The ​discovery ​of ​reprogramming ​methods ​that ​rely ​on ​defined ​transcription ​factors ​and ​their ​use ​in ​the ​derivation ​of ​ patient-specific ​iPS ​cell ​lines ​have ​greatly ​expanded ​the ​ potential ​utility ​of ​pluripotent ​cells. ​Patient-specific ​iPS ​ cells ​have ​already ​enabled ​in ​vitro ​studies ​of ​diseases ​ including ​spinal ​muscular ​atrophy, ​familial ​dysautonomia ​and ​ LEOPARD ​syndrome. ​Future ​applications ​of ​human ​pluripotent ​stem ​ cell ​lines ​could ​also ​include ​the ​study ​of ​common ​diseases ​ that ​arise ​as ​the ​result ​of ​complex ​interactions ​between ​a ​ patient’s ​genotype ​and ​their ​environment. ​Finally, ​pluripotent ​ cells ​will ​eventually ​serve ​as ​a ​renewable ​source ​of ​both ​ autologous ​cells ​and ​tissue ​for ​transplantation ​and ​regenerative ​medicine.

Our inaugural symposium will feature world leaders who will describe their latest advances in stem cell biology and reprogramming.

**Featured speakers:**  
***Amander Clark***  
***Stephen Dalton***  
***Kevin Eggan***  
***Jacob Hanna***  
***Konrad Hochedlinger***  
***Alexander Meissner***  
***Tarjei Mikkelsen***  
***Huck Hui Ng***  
***Kathrin Plath***  
***John Rinn***  
***Joseph Wu***  
***Ken Zaret***  
***Thomas Zwaka***

Registration and more information at broad.io/prs2015



 

 

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