Know the Players: Combinatorial, Single-Cell Approaches to Explore the Complexity of Biologic Systems

Click here to register for this free webinar.

Presented by:
Jonthan M. Irish, PhD
Assistant Professor, Department of Cancer Biology
Vanderbilt University

Manish Ray, PhD
Single-cell Analysis Expert
Fluidigm

You will learn:
• Importance and relevance of single-cell approaches to cancer research
• Cytomic techniques for single-cell analysis
• Quality controls for cytomics techniques

Cutting-edge single-cell analysis tools for exploring the genomic, transcriptomic and proteomic states of both tumor and related immune cells are enabling researchers to understand system heterogeneity, identify cells with previously unrecognized phenotypes and elucidate important therapeutic mechanisms.

Jonathan Irish will present his work on human solid tumor cytomics, which is revealing novel melanoma and immune cell subsets. He will highlight high-content single-cell approaches developed by his lab for systems immunology and cancer biology studies of human solid tumors, including melanoma and brain cancer. Dr. Irish will also discuss technical and biological quality controls, computational analysis and the strengths of combining single-cell approaches, such as mass cytometry, phospho-flow, imaging, transcript profiling and sequencing. These cytomic approaches are especially powerful for dissecting cellular mechanisms of treatment response, monitoring key biomarkers and precise targeting of clinically relevant cell subsets.

Manisha Ray will guide you through the newest Fluidigm technologies for single cell analysis at the genomic, proteomic and transcriptomic levels.