# HSCI Stem Cells & Cancer in the Skin & Solid Organs Symposium 2022 #### calendar\_today Date and Time **September 15 - September 16, 2022** All day #### pin\_drop Location **Joseph B. Martin Conference Center, 77 Avenue Louis Pasteur, Boston, MA** ![Cancer Skin Symposium](/sites/g/files/omnuum10026/files/styles/hwp_1_1__720x720_scale/public/hsci/files/screen_shot_2022-08-16_at_4.52.00_pm.png?itok=C_xZ-Ch3) [HSCI Cancer Disease Program](https://urldefense.proofpoint.com/v2/url?u=https-3A__harvard.us19.list-2Dmanage.com_track_click-3Fu-3D6462e89f312befb995e43ed10-26id-3D0739450828-26e-3Dc41264fe18&d=DwMFaQ&c=WO-RGvefibhHBZq3fL85hQ&r=lc5VH9_k07cnpVDODzbcuESf_y4wdRs8-sO1GWo9tMk&m=pSQl8vEKqOqqfWD34nVUxvnwKmTnqMfMTDRXniEb7FdCAP1KZXVuNtl-672Icnwn&s=sN1h3-n9Q5gYsd2fhR3AC92kJq7kACcGh1b-JW7pb5E&e=) Leaders [Carla F. Kim, PhD](https://urldefense.proofpoint.com/v2/url?u=https-3A__harvard.us19.list-2Dmanage.com_track_click-3Fu-3D6462e89f312befb995e43ed10-26id-3Dd511c7d721-26e-3Dc41264fe18&d=DwMFaQ&c=WO-RGvefibhHBZq3fL85hQ&r=lc5VH9_k07cnpVDODzbcuESf_y4wdRs8-sO1GWo9tMk&m=pSQl8vEKqOqqfWD34nVUxvnwKmTnqMfMTDRXniEb7FdCAP1KZXVuNtl-672Icnwn&s=MxJGD0zCBpqUb0SqOaLPNCa8CDbYzEM2aCU1Lrwn1B0&e=) and [Mario Suva, MD, PhD](https://urldefense.proofpoint.com/v2/url?u=https-3A__harvard.us19.list-2Dmanage.com_track_click-3Fu-3D6462e89f312befb995e43ed10-26id-3Db9140e2bcd-26e-3Dc41264fe18&d=DwMFaQ&c=WO-RGvefibhHBZq3fL85hQ&r=lc5VH9_k07cnpVDODzbcuESf_y4wdRs8-sO1GWo9tMk&m=pSQl8vEKqOqqfWD34nVUxvnwKmTnqMfMTDRXniEb7FdCAP1KZXVuNtl-672Icnwn&s=fU0vUzXz2Qfim8DSdyMx76L89AfYmZe4ss9Xu1OO5wQ&e=), and [HSCI Skin Disease Program](https://urldefense.proofpoint.com/v2/url?u=https-3A__harvard.us19.list-2Dmanage.com_track_click-3Fu-3D6462e89f312befb995e43ed10-26id-3Da2eb1ac757-26e-3Dc41264fe18&d=DwMFaQ&c=WO-RGvefibhHBZq3fL85hQ&r=lc5VH9_k07cnpVDODzbcuESf_y4wdRs8-sO1GWo9tMk&m=pSQl8vEKqOqqfWD34nVUxvnwKmTnqMfMTDRXniEb7FdCAP1KZXVuNtl-672Icnwn&s=YlVzbiSGwK37m3GV4JpTMd3avZa6fQzA3JpXs0TLY1Q&e=) Leaders [Markus Frank, MD](https://urldefense.proofpoint.com/v2/url?u=https-3A__harvard.us19.list-2Dmanage.com_track_click-3Fu-3D6462e89f312befb995e43ed10-26id-3D378d64ae0c-26e-3Dc41264fe18&d=DwMFaQ&c=WO-RGvefibhHBZq3fL85hQ&r=lc5VH9_k07cnpVDODzbcuESf_y4wdRs8-sO1GWo9tMk&m=pSQl8vEKqOqqfWD34nVUxvnwKmTnqMfMTDRXniEb7FdCAP1KZXVuNtl-672Icnwn&s=B_vioKZOeedc9M_OY6nzd5xUFPGAmObX2uBJ-LwQZg8&e=) and [George F. Murphy, MD](https://urldefense.proofpoint.com/v2/url?u=https-3A__harvard.us19.list-2Dmanage.com_track_click-3Fu-3D6462e89f312befb995e43ed10-26id-3Df958426c5b-26e-3Dc41264fe18&d=DwMFaQ&c=WO-RGvefibhHBZq3fL85hQ&r=lc5VH9_k07cnpVDODzbcuESf_y4wdRs8-sO1GWo9tMk&m=pSQl8vEKqOqqfWD34nVUxvnwKmTnqMfMTDRXniEb7FdCAP1KZXVuNtl-672Icnwn&s=M6ewbzxhjI2FCRXGnwI7HPBz5u3Zn-gKUMhMQnujgPI&e=) have planned an exciting 2-day symposium, including talks by leading researchers from our community and other institutions including keynotes from [Robert M. Lavker, PhD](https://urldefense.proofpoint.com/v2/url?u=https-3A__harvard.us19.list-2Dmanage.com_track_click-3Fu-3D6462e89f312befb995e43ed10-26id-3Daabf78438a-26e-3Dc41264fe18&d=DwMFaQ&c=WO-RGvefibhHBZq3fL85hQ&r=lc5VH9_k07cnpVDODzbcuESf_y4wdRs8-sO1GWo9tMk&m=pSQl8vEKqOqqfWD34nVUxvnwKmTnqMfMTDRXniEb7FdCAP1KZXVuNtl-672Icnwn&s=dXI2B8VYhNoPn4IMRiXpMsWZ3LHH-l1w1dqPugZPfXw&e=) and [Irving Weissman, MD](https://urldefense.proofpoint.com/v2/url?u=https-3A__harvard.us19.list-2Dmanage.com_track_click-3Fu-3D6462e89f312befb995e43ed10-26id-3Dc245e351a0-26e-3Dc41264fe18&d=DwMFaQ&c=WO-RGvefibhHBZq3fL85hQ&r=lc5VH9_k07cnpVDODzbcuESf_y4wdRs8-sO1GWo9tMk&m=pSQl8vEKqOqqfWD34nVUxvnwKmTnqMfMTDRXniEb7FdCAP1KZXVuNtl-672Icnwn&s=PqYQrygRh2E39ZOtgkF87GPRKnS9AGhW0Y1tpNJcw78&e=). *The HSCI Cancer Program will be featured as first day of a two days Symposium and will be followed by the HSCI Skin Program. The HSCI Cancer Program will cover the evolution of the stem cell model of cancer through the lens of state-of-art technologies such as single-cell multi-omics and epigenomics. We will discuss metabolic dependencies of malignant stem cells and their specific interactions with the immune system. The symposium will feature speakers and posters selected from abstracts.* *The HSCI Skin Program brings together local expertise and national prominence in skin stem cell biology with special emphasis on updating current, state-of-the-art knowledge. Represented are discoverers and innovators responsible for the first isolation of stem cells, for the discovery of epidermal and follicular stem cells and of dermal mesenchymal stem cells, for developing biodegradable microenvironments that promote stem cell-driven regeneration and organoids capable of growing hair, for epithelial stem cell manipulation capable of restoring vision, and for the discovery of skin cancer (melanoma) stem cells.* *This intensive, two-day experience represents a unique opportunity to acquire insight and expertise in the role of stem cells in regenerative medicine, inflammation, and cancer.* *Designed as in-person event, it seeks to bring together the local scientific community to set the stage for future collaborations. The back-to-back structure is meant to foster further interactions across the wider HSCI community.* ## [RSVP HERE](https://docs.google.com/forms/d/e/1FAIpQLSfjvuhC5yrv8Z2ZE5oO2CGHZ3VDUcObNqvV_QrZmMZcZuO-7A/viewform) **Thursday, September 15** 9:00-9:10am Welcome | HSCI Cancer Program Leaders [Carla Kim, PhD](/people/carla-f-kim-phd) Boston Children's Hospital [Mario Suva, MD, PhD](/people/mario-suva-md-phd) Massachusetts General Hospital 9:10-9:55am [Bradley Bernstein, MD, PhD](https://bernstein.dfci.harvard.edu) Dana-Farber Cancer Institute *Modeling epigenetic lesions that cause glioma* 9:55-10:40am Marcos Simoes-Costa, PhD Boston Children's Hospital *Metabolic regulation of the neural crest epigenome* 10:40-10:55am | Break 10:55-11:40am [Dan Landau, MD, PhD](https://www.landaulab.org) Weill Cornell Medical College, New York Genome Center *Somatic evolution mapped with single-cell multi-omics* 11:40am-12:25pm | Poster Session 12:25-1:25pm | LUNCH 1:25-2:10pm [Judith Agudo, PhD](https://www.dfhcc.harvard.edu/insider/member-detail/member/judith-agudo-phd/) Dana-Farber Cancer Institute Quiescent cancer stem cells evade anti-tumor immunity 2:10-2:55pm [Jason Buenrostro, PhD](https://www.buenrostrolab.com) Harvard University, Department of Stem Cell and Regenerative Biology *Single-cell Epigenomics: Gene regulation at unprecedented resolution* 2:55-3:10pm | Break 3:10-3:55pm [Nada Kalaany, PhD](https://www.kalaanylab.org/lab-members.html) Boston Children's Hospital *Metabolic Dependencies in Pancreatic Cancer* 3:55-4:05pm Thank you and Closing | Carla Kim and Mario Suva 4:00-5:00 | Social Hour **Friday, September 16** 8:00-8:05am Opening Remarks 8:05-9:00am Opening Keynote Speaker [Robert Lavker, PhD](https://www.feinberg.northwestern.edu/faculty-profiles/az/profile.html?xid=15002) Northwestern University Feinberg School of Medicine *Epithelial Stem Cells: Adventures in Dermato-ophthalmology* 9:00-9:45am [Karl Koehler, PhD](https://koehler-lab.org) Boston Children's Hospital *Modeling Human Skin Development* 9:45-10:30am [Ya-Chieh Hsu, PhD](/people/ya-chieh-hsu-phd) Harvard University, Department of Stem Cell and Regenerative Biology *Skin Deep: Stem Cells at the Nexus of the Niche, Physiology, and the External Environment* 10:30-10:45am | Break 10:45-11:30am [Dennis Orgill, MD, PhD](https://physiciandirectory.brighamandwomens.org/details/1219/dennis-orgill-plastic_surgery-boston) Brigham and Women's Hospital *Skin Regeneration, from Bench to Bedside in 40 Years* 11:30am-12:15pm [George F. Murphy, MD](/people/george-f-murphy-md) Brigham and Women's Hospital *Skin Stem Cells as Effectors and Targets: New Insights from Psoriasis and GVHD* 12:15-1:15pm | LUNCH 1:15-2:00pm [Natasha Frank, MD](https://physiciandirectory.brighamandwomens.org/details/588/natasha-frank-genetics-boston) Brigham and Women's Hospital *Developmental Plasticity of ABCB5-positive Stem Cells* 2:00-2:45pm [Tobias Schatton, PhD, PharmD](https://connects.catalyst.harvard.edu/Profiles/display/Person/33169) Brigham and Women's Hospital *Leveraging Glyco-immuno-oncology for Optimizing Immune Checkpoint Therapy via Cell Type-directed Targeting* 2:45-3:00pm | Break 3:00-3:45pm [Bruce Ksander, PhD](https://eye.hms.harvard.edu/bruceksander) Harvard Medical School, Department of Ophthalmology *In Vivo Epigenetic Reprogramming to Reverse Age and Rejuvenate Cellular Functions* 3:45-4:30pm [Markus Frank, MD](/people/markus-frank-md) Boston Children's Hospital *The Therapeutic Promise of Dermal Mesenchymal Stem Cells* 4:30-5:30pm Closing Keynote Speaker [Irving Weissman, MD](https://med.stanford.edu/stemcell/institutefaculty/weissman.html) Stanford Medicine, Institute for Stem Cell Biology and Regenerative Medicine *Normal and Neoplastic Stem Cells* 5:30-6:00pm Round Table Discussion: *The Next Frontiers* See also:- [ Cancer Program Events ](/event-program/cancer-program-events) - [ Skin Program Event ](/event-program/skin-program) - [ For the Public ](/event-type/public) Share on:- [ Facebook ](#) - [ Twitter ](#) - [ Linkedin ](#) Save: [ Add to calendar calendar\_today ](https://www.hsci.harvard.edu/node/1650103/event-feed.ics) Copy link link