Brigham and Women's Hospital

The Van Galen Laboratory studies normal and malignant hematopoiesis, with a focus on hematopoietic stem cell aging and the development of acute myeloid leukemia. Our projects span age-associated inflammatory pathways, targeted therapies for leukemia, and...

The Lehoczky lab is anchored in thinking about why mammals do not regenerate their limbs following amputation.

Intriguingly, some mammalian digit tips (including mouse and human children) can regenerate following amputation, demonstrating that mammals...

The Ebert lab focuses on the molecular basis and treatment of hematologic malignancies, with a particular focus on myelodysplastic syndromes (MDS).

In large-scale genetic analyses of patient samples, the lab has identified somatic mutations that predict...

The Young-Pearse lab uses molecular approaches to study the functions of genes involved in neurodegenerative and neurodevelopmental diseases.

Tracy Young-Pearse's research group focuses on two main areas.

The identification of novel therapeutic targets for...

Vik Khurana M.D. Ph.D. is the inaugural incumbent of the Tracy T. Batchelor Endowed Chair in Neurology at MassGeneral Brigham, Chief of the Movement Disorders Division at Brigham and Women's Hospital and Associate Professor of Neurology at Harvard

Markus Frank's laboratory defined a novel function for ABCB5 in cancer stem cell maintenance and tumor growth, and investigates the therapeutic efficacy of ABCB5 targeting in melanoma and additional ABCB5-expressing human malignancies.

Research in the...

The Murphy lab studies scarless healing during fetal development and “stem cell burnout” during aging, with the goal of coaxing skin stem cells into healing wounds by regenerating tissue instead of forming a scar.

The Murphy Laboratory focuses on...

Overview:

Our laboratory investigates the origin, development, and differentiation of hematopoietic stem cells (HSCs) to treat patients with leukemia, lymphoma, genetic blood disorders, and bone-marrow failure syndromes. We have expertise in utilizing...

The Pourquié laboratory is a world leader in vertebrate musculo-skeletal axis development.

We are interested in the development of the vertebrate musculo-skeletal axis. Using chicken and mouse embryos as model systems, we combine developmental biology and...

Yick Fong's research aims to elucidate the full repertoire of transcription factors operating in stem cells, so that the full potential of stem cells in tissue regeneration and replacement therapy can be realized.

We study key transcriptional and gene...