# Seed Grants 2012 ## expand\_more Sort**Project Lead** **Affiliation** **Title** **Research Area** Susan Dymecki, MD, PhD Harvard Medical School Reverse engineering serotonin neuron subtypes Neuronal Disorders Stephen Haggarty, PhD Massachusetts General Hospital Characterization of iPSC-derived neurons from patients with intellectual disability: role of TCF4 in Pitt-Hopkins Syndrome Neuronal Disorders Bernhard Kuhn, MD Boston Children's Hospital Controlling the differentiation of ES and iPS-derived heart muscle cells Cardiovascular Disease Rohit Kulkarni, MD, PhD Joslin Diabetes Center Significance of MODY genes in the differentiation of human iPS cells into insulin-secreting beta cells Diabetes Cammie Lesser, MD, PhD Massachusetts General Hospital Non-viral transdifferentiation of fibroblasts to cardiomyocytes Cardiovascular Diseases Michael Mannstadt, MD Massachusetts General Hospital Directed differentiation of ES and iPS cells towards parathyroid cells Endocrine Disorders Thomas Serwold, PhD Joslin Diabetes Center Identification and functional characterization of thymic epithelial stem cells and progenitors Immunology Matthew Steinhauser, MD Brigham and Women’s Hospital Quantifying human cell division with a heavy water tracer Cellular Imaging Clifford Tabin, PhD Harvard Medical School Analysis of blastema cell heterogeneity by RNA-seq Tissue Regeneration & Repair Tracy Young-Pearse, PhD Brigham and Women’s Hospital Establishment of a single cell assay to screen individual cell types for efficacy of putative small molecule drugs Single-Cell Analysis