Seed Grants 2012

Susan Dymecki, MD, PhD

Harvard Medical School

Reverse engineering serotonin neuron subtypes

Neuronal Disorders

Stephen Haggarty, PhD

Massachusetts General Hospital

Characterization of iPSC-derived neurons from patients with intellectual disability: role of TCF4 in Pitt-Hopkins Syndrome

Neuronal Disorders

Bernhard Kuhn, MD

Boston Children's Hospital

Controlling the differentiation of ES and iPS-derived heart muscle cells

Cardiovascular Disease

Rohit Kulkarni, MD, PhD

Joslin Diabetes Center

Significance of MODY genes in the differentiation of human iPS cells into insulin-secreting beta cells

Diabetes

Cammie Lesser, MD, PhD

Massachusetts General Hospital

Non-viral transdifferentiation of fibroblasts to cardiomyocytes

Cardiovascular Diseases

Michael Mannstadt, MD

Massachusetts General Hospital

Directed differentiation of ES and iPS cells towards parathyroid cells

Endocrine Disorders

Thomas Serwold, PhD

Joslin Diabetes Center

Identification and functional characterization of thymic epithelial stem cells and progenitors

Immunology

Matthew Steinhauser, MD

Brigham and Women’s Hospital

Quantifying human cell division with a heavy water tracer

Cellular Imaging

Clifford Tabin, PhD

Harvard Medical School

Analysis of blastema cell heterogeneity by RNA-seq

Tissue Regeneration & Repair

Tracy Young-Pearse, PhD

Brigham and Women’s Hospital

Establishment of a single cell assay to screen individual cell types for efficacy of putative small molecule drugs

Single-Cell Analysis