Seed Grants 2011

Project Lead
Affiliation
Title
Disease Area
Wolfram Goessling, MD, PhD
Brigham and Women's Hospital
Functional characterization of genes associated with abnormal liver tests for liver development and repair – a post-GWAS approach
Liver Disease
Stanley Shaw, MD, PhD
Massachusetts General Hospital
Small molecule inhibitors of p16INK4a: proof-of-concept for the generation of iPS cells via a high-throughput screening platform
Cardiovascular Disease
Carla F. Kim, PhD
Boston Children's Hospital
Imprinted gene regulation in lung and skin stem cell self-renewal
Cancer
Elliot Chaikof, MD, PhD
Beth Israel Deaconess Medical Center
Engineered fascia for stem cell therapy in hernia repair
Hernia
Rakesh Karmacharya, MD, PhD
McLean Hospital
Identification of cellular signatures for schizophrenia in iPSC-derived neuronal cells
Neuropsychiatric Diseases
Sandra McAllister, PhD
Brigham and Women's Hospital
Understanding how systemic factors govern breast cancer stem cell plasticity and malignancy
Cancer
Chien-Wei (Eric) Liao, MD, PhD
Massachusetts General Hospital
Transcriptome and functional analysis of neural crest stem cell
Genetic Diseases
Xu Wu, PhD
Massachusetts General Hospital
Controlling stem cell self-renewal and differentiation using small molecule modulators of hippo signaling pathway
Cancer
Jordan A. Kreidberg, MD
Boston Children's Hospital
Reprogramming ES and IPS cells into kidney progenitor cells
Kidney Disease
Joy Wu, MD, PhD
Massachusetts General Hospital
Chemical screening of pluripotent stem cells for modifiers of mesenchymal lineage commitment
Osteoporosis