#  Seed Grants 2007 

 



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Sort**Project Lead**

**Affiliation**

**Title**

**Disease Area**

Li Chai, MD

Brigham and Women's Hospital

SALL4 Dependent Transcriptional Network in Human and Murine Embryonic Stem Cells

Cancer

Zheng-Yi Chen, PhD

Massachusetts General Hospital

Inner ear stem cell genes: identification, function and role in hair cell regeneration

Hearing Loss

Dieter Egli, PhD

Faculty of Arts and Sciences, Harvard University

Derivation of patient specific human embryonic stem cell lines by chromosome transfer into human zygotes and blastomeres

Genetic Diseases

Benjamin Humphreys, MD, PhD

Brigham and Women's Hospital

Epithelial Cell Lineage Analysis During Renal Repair

Kidney Disease

Richard I. Gregory, PhD

Children's Hospital Boston

Promoting stem cell expansion through chemical inhibition of microRNA-mediated cell differentiation

Genetic Diseases

Carla F. Kim, PhD

Children's Hospital Boston

Lineage tracing of lung stem cells in vivo & in vitro

Lung Disease

Kameran Lashkari, MD

The Schepens Eye Research Institute

Application of retinal progenitor cells derived from eyes with persistent fetal vasculature to replace lost retinal ganglion cells in clinical glaucoma

Eye Diseases

Stuart H. Orkin, MD

Dana-Farber Cancer Institute

Down Syndrome, somatic mutation of GATA-1, and acute megakaryoblastic (M7 AML) leukemia

Cancer

Sridhar Rao, MD, PhDIbrahim Domian, MD, PhD

Dana-Farber Cancer Institute  
 Massachusetts General Hospital

Identification of Master Transcriptional Regulators for Early Lineage Commitment

Cancer

Sabina Signoretti, MD

Brigham & Women's Hospital

Identification of stem cells in prostate and bladder epithelia

Urinary Diseases