In 2007, Christine Mummery, PhD, became the first Harvard Stem Cell Institute Radcliffe Fellow.

The Harvard Stem Cell Institute and the Radcliffe Institute for Advanced Study have collaborated to offer sponsorship for up to one Harvard Stem Cell Institute Radcliffe Fellow per year through the Radcliffe Institute's well-established and world-renowned fellowship program.   HSCI is interested in supporting advanced fellowship work that involves or relates to the field of stem cell science.  Radcliffe is likewise interested in expanding its fellowships' scope of interest to attract more science-related and interdisciplinary study.

In addition to the Radcliffe Institute's standards for Fellow eligibility, HSCI Fellow's work must relate to stem cell science and be interdisciplinary, showing integration of stem cell science into two or more disciplines.  Appropriate fields of specialization for candidates for the HSCI Radcliffe Fellowship include, but are not limited to, education, journalism, law, philosophy, political science, religion, science, science writing, and sociology.  Applicants are not required to, but may, have experience in stem cell research.   Bench science may, but need not be, a component of the proposal.  Fellowship applicants from all disciplines and areas of expertise are encouraged to apply.

Applicants with a science or math background should apply through the Natural Scientists and Mathematicians program; all others should apply through the Creative Artists, Humanists, and Social Scientists program: Radcliffe Fellowship Application.  Applicants who reach the final round of selection, and who also meet the HSCI criteria will be considered for HSCI sponsorship.

As sponsor, HSCI will support the full cost of the fellowship.  The Harvard Stem Cell Institute Radcliffe Fellow will be part of the Radcliffe Fellow community and will also be made a member of the HSCI community, with associated access to HSCI programs, lecture series, inter-lab meetings, etc.  The Fellow will have the opportunity to interact with members of the over 75 stem cell researchers and faculty affiliated with the HSCI.   The Fellow will also be invited to report to the HSCI Executive Committee and to present at HSCI events as appropriate.  

2007 HSCI Radcliffe Fellow

Christine L. Mummery, PhD  
Senior Scientist, Hubrecht Laboratory, University of Utrecht
PhD, Biophysics, Guy's Hospital Medical School, University of London
BSc with Honors, Physics, University of Nottingham, UK 
Fellowship Project Title: Engineering the right scaffold: How matrix flexibility may determine cardiac cell fate
Summary: To address the question of whether cell fate during the differentiation of stem cells to cardiomyocytes is controlled by the physical properties of the environment by engineering substrates of different elasticity and determining which cell types are formed.  The purpose is to improve mass production of heart cells with the right properties for future drug screens and transplantation.  
Collaborations: Dr. Kit Parker, Assistant Professor of Biomedical Engineering, School of Engineering and Applied Sciences, Harvard University; Dr. Ken Chien, Director, MGH Cardiovascular Research Center

"We warmly welcome the expertise Dr. Mummery has to offer on the differentiation of stem cells into cardiomyocytes and their expansion in culture into our groups at Harvard and look forward to integrating our skills in tissue engineering, cardiac physiology, and cardiac development with hers to advance this field towards new cell-based therapies and biomarker discovery." - Dr. Kenneth Chien, MD PhD; Director, MGH Cardiovascular Research Center; Charles Addison and Elizabeth Ann Sanders Professor; Professor of Medicine, Harvard Medical School; Principal Faculty, Harvard Stem Cell Institute

Dr. Mummery was the keynote speaker at the inaugural HSCI Cardiovascular Program Think Tank on Monday, April 30, 2007 at the Radcliffe Gym.  Christine presented on "Cardiomyocyte differentiation of human embryonic stem cells:  transplantation, development and disease."