| Review and Commentary | Woods IG, Schier AF. Targeted mutagenesis in zebrafish. Nat Biotechnol. 2008 Jun;26(6):650-1. | 06/2008 | Nat Biotechnol | |
| Review and Commentary | Zon LI. Self-renewal and differentiation at Cell Stem Cell. Cell Stem Cell. 2008 Jun 5;2(6):510. | 06/2008 | Cell Stem Cell | |
| Review and Commentary | Traum AZ, Kawai T, Vacanti JP, Sachs DH, Cosimi AB, Madsen JC. The need for tolerance in pediatric organ transplantation. Pediatrics. 2008 Jun;121(6):1258-60. | 06/2008 | Pediatrics | |
| Review and Commentary | Korngold EC, Jaffer FA, Weissleder R, Sosnovik DE. Noninvasive imaging of apoptosis in cardiovascular disease. Heart Fail Rev. 2008 Jun;13(2):163-73. | 06/2008 | Heart Fail Rev | |
| Blood | Guo F, Cancelas JA, Hildeman D, Williams DA, Zheng Y. Rac GTPase isoforms, Rac1 and Rac2, play a redundant and crucial role in T-cell development. Blood. 2008 Jun 25. | 06/2008 | Blood | |
| Blood | Zhang X, Shang X, Guo F, Murphy K, Kirby M, Kelly P, Reeves L, Smith FO, Williams DA, Zheng Y, Pang Q. Defective homing is associated with altered Cdc42 activity in cells from Fanconi anemia group A patients. Blood. 2008 Jun 18. | 06/2008 | Blood | |
| Blood | Dooley KA, Fraenkel PG, Langer NB, Schmid B, Davidson AJ, Weber G, Chiang K, Foott H, Dwyer C, Wingert RA, Zhou Y, Paw BH, Zon LI. 2000 Screen Consortium. montalcino, A zebrafish model for variegate porphyria. Exp Hematol. 2008 Jun 10. | 06/2008 | Exp Hematol | |
| Blood | Wang Y, Yabuuchi A, McKinney-Freeman S, Ducharme DM, Ray MK, Chawengsaksophak K, Archer TK, Daley GQ. Cdx gene deficiency compromises embryonic hematopoiesis in the mouse. Proc Natl Acad Sci USA. 2008 Jun 3;105(22):7756-61. Epub 2008 May 29. | 06/2008 | Proc Natl Acad Sci USA | |
| Blood | Armistead PM, Mohseni M, Gerwin R, Walsh EC, Iravani M, Chahardouli B, Rostami S, Zhang W, Neuberg D, Rioux J, Ghavamzadeh A, Ritz J, Antin JH, Wu CJ. Erythroid-lineage-specific engraftment in patients with severe hemoglobinopathy following allogeneic hematopoietic stem cell transplantation. Exp Hematol. 2008 Jun 10. | 06/2008 | Exp Hematol | |
| Blood | Janzen V, Fleming HE, Riedt T, Karlsson G, Riese MJ, Lo Celso C, Reynolds G, Milne CD, Paige CJ, Karlsson S, Woo M, Scadden DT. Hematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3. Cell Stem Cell. 2008 Jun 5;2(6):584-94. | 06/2008 | Cell Stem Cell | |
| Cancer | Scaglioni PP, Yung TM, Choi SC, Baldini C, Konstantinidou G, Pandolfi PP. CK2 mediates phosphorylation and ubiquitin-mediated degradation of the PML tumor suppressor. Mol Cell Biochem. 2008 Jun 20. | 06/2008 | Mol Cell Biochem | |
| Cancer | Tam WF, Gu TL, Chen J, Lee BH, Bullinger L, Frohling S, Wang A, Monti S, Golub TR, Gilliland DG. Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells. Blood. 2008 Jun 17. | 06/2008 | Blood | |
| Cancer | Yamada Y, Sanchez-Aguilera A, Brandt EB, McBride M, Al-Moamen NJ, Finkelman FD, Williams DA, Cancelas JA, Rothenberg ME. FIP1L1/PDGFR{alpha} synergizes with SCF to induce systemic mastocytosis in a murine model of chronic eosinophilic leukemia/hypereosinophilic syndrome. Blood. 2008 Jun 6. | 06/2008 | Blood | |
| Cancer | Walkley CR, Qudsi R, Sankaran VG, Perry JA, Gostissa M, Roth SI, Rodda SJ, Snay E, Dunning P, Fahey FH, Alt FW, McMahon AP, Orkin SH. Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease. Genes Dev. 2008 Jun 15;22(12):1662-1676. | 06/2008 | Genes Dev | |
| Cardiovascular System | Zhou B, Ma Q, Rajagopal S, Wu SM, Domian I, Rivera-Feliciano J, Jiang D, von Gise A, Ikeda S, Chien KR, Pu WT. Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart. Nature. 2008 Jun 22. | 06/2008 | Nature | |
| Cardiovascular System | Adams JW, Wang J, Davis JR, Liaw C, Gaidarov I, Gatlin J, Dalton ND, Gu Y, Ross Jr JR, Behan D, Chien KR, Connolly D. Myocardial expression, signaling, and function of GPR22; A protective role for an orphan G-protein coupled receptor. Am J Physiol Heart Circ Physiol. 2008 Jun 6. | 06/2008 | Am J Physiol Heart Circ Physiol | |
| Cardiovascular System | Geier C, Gehmlich K, Ehler E, Hassfeld S, Perrot A, Hayess K, Cardim N, Wenzel K, Erdmann B, Krackhardt F, Posch MG, Bublak A, Nagele H, Scheffold T, Dietz R, Chien KR, Spuler S, Farst DO, Narnberg P, Ozcelik C. Beyond the sarcomere: CSRP3 mutations cause hypertrophic cardiomyopathy. Hum Mol Genet. 2008 Jun 2. | 06/2008 | Hum Mol Genet | |
| Developmental Biology | Piskounova E, Viswanathan SR, Janas M, Lapierre RJ, Daley GQ, Sliz P, Gregory RI. Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28. J Biol Chem. 2008 Jun 12. | 06/2008 | J Biol Chem | |
| Developmental Biology | Lu J, Guo S, Ebert BL, Zhang H, Peng X, Bosco J, Pretz J, Schlanger R, Wang JY, Mak RH, Dombkowski DM, Preffer FI, Scadden DT, Golub TR. MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors. Dev Cell. 2008 Jun;14(6):843-53. | 06/2008 | Dev Cell | |
| Developmental Biology | Lu CW, Yabuuchi A, Chen L, Viswanathan S, Kim K, Daley GQ. Ras-MAPK signaling promotes trophectoderm formation from embryonic stem cells and mouse embryos. Nat Genet. 2008 Jul;40(7):921-6. Epub 2008 Jun 8. | 06/2008 | Nat Genet | |
| Diabetes | Bonner-Weir S, Inada A, Yatoh S, Li WC, Aye T, Toschi E, Sharma A. Transdifferentiation of pancreatic ductal cells to endocrine beta-cells. Biochem Soc Trans. 2008 Jun;36(Pt 3):353-6. | 06/2008 | Biochem Soc Trans | |
| Diabetes | Butty V, Campbell C, Mathis D, Benoist C; the Diabetes Prevention Trial-Type 1 Study Group. Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the DPT1 trial. Diabetes. 2008 Jun 12. | 06/2008 | Diabetes | |
| Imaging | Taktak S, Weissleder R, Josephson L. Electrode Chemistry Yields a Nanoparticle-Based NMR Sensor for Calcium. Langmuir. 2008 Jun 18. | 06/2008 | Langmuir | |
| Imaging | Farrar CT, Dai G, Novikov M, Rosenzweig A, Weissleder R, Rosen BR, Sosnovik DE. Impact of field strength and iron oxide nanoparticle concentration on the linearity and diagnostic accuracy of off-resonance imaging. NMR Biomed. 2008 Jun;21(5):453-63. | 06/2008 | NMR Biomed | |
| Immunology | Johnsen AK, Plenge RM, Butty V, Campbell C, Dieguez-Gonzalez R, Gomez-Reino JJ, Shadick N, Weinblatt M, Gonzalez A, Gregersen PK, Benoist C, Mathis D. A broad analysis of IL1 polymorphism and rheumatoid arthritis. Arthritis Rheum. 2008 Jun 24;58(7):1947-1957. | 06/2008 | Arthritis Rheum | |
| Immunology | Sama MA, Mathis DM, Furman JL, Mohmmad Abdul H, Artiushin IA, Kraner SD, Norris CM. Interleukin-1beta -dependent signaling between astrocytes and neurons depends critically on astrocytic calcineurin/nfat activity. J Biol Chem. 2008 Jun 9. | 06/2008 | J Biol Chem | |
| Nervous System | Taylor AL, Bonventre JV, Uliasz TF, Hewett JA, Hewett SJ. Cytosolic Phospholipase A(2)alpha Inhibition Prevents Neuronal NMDA Receptor-Stimulated Arachidonic Acid Mobilization and Prostaglandin Production but not Subsequent Cell Death. J Neurochem. 2008 Jun 17. | 06/2008 | J Neurochem | |
| Nervous System | de Chevigny A, Cooper O, Vinuela A, Reske-Nielsen C, Lagace DC, Eisch AJ, Isacson O. Fate Mapping and Lineage Analyses Demonstrate the Production of a Large Number of Striatal Neuroblasts after TGF{alpha} and Noggin Striatal Infusions into the Dopamine-depleted Striatum. Stem Cells. 2008 Jun 12. | 06/2008 | Stem Cells | |
| Nervous System | Rodino-Klapac LR, Lee JS, Mulligan RC, Clark KR, Mendell JR. Lack of toxicity of alpha-sarcoglycan overexpression supports clinical gene transfer trial in LGMD2D. Neurology. 2008 Jun 18. | 06/2008 | Neurology | |
| Technology | Huangfu D, Maehr R, Guo W, Eijkelenboom A, Snitow M, Chen AE, Melton DA. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat Biotechnol. 2008 Jun 22. | 06/2008 | Nat Biotechnol | |
| Tissue Engineering | Steigman SA, Armant M, Bayer-Zwirello L, Kao GS, Silberstein L, Ritz J, Fauza DO. Preclinical regulatory validation of a 3-stage amniotic mesenchymal stem cell manufacturing protocol. J Pediatr Surg. 2008 Jun;43(6):1164-9. | 06/2008 | J Pediatr Surg | |
| Review and Commentary | Faber J, Gregory RI, Armstrong SA. Linking miRNA regulation to BCR-ABL expression: the next dimension. Cancer Cell. 2008 Jun;13(6):467-9. | 06/2008 | Cancer Cell | |
| Chien KR. Regenerative medicine and human models of human disease. Nature. 2008 May 15;453(7193):302-5. | 05/2008 | Nature | |
| Carracedo A, Salmena L, Pandolfi PP. SnapShot: PTEN signaling pathways. Cell. 2008 May 2;133(3):550.e1. | 05/2008 | Cell | |
| Salmena L, Carracedo A, Pandolfi PP. Tenets of PTEN tumor suppression. Cell. 2008 May 2;133(3):403-14. | 05/2008 | Cell | |
| Sadelain M, Williams DA. A "vector drain" in US gene therapy development? Mol Ther. 2008 May;16(5):801-2. No abstract available. | 05/2008 | Mol Ther | |
| Monach PA, Mathis D, Benoist C. The K/BxN arthritis model. Curr Protoc Immunol. 2008 May;Chapter 15:Unit 15.22. | 05/2008 | Curr Protoc Immunol | |
| Zon LI. Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal. Nature. 2008 May 15;453(7193):306-13. | 05/2008 | Nature | |
| Pfister O, Liao R. Pump to survive: novel cytoprotective strategies for cardiac progenitor cells. Circ Res. 2008 May 9;102(9):998-1001. | 05/2008 | Circ Res | |
| Hoganson DM, Pryor HI 2nd, Vacanti JP. Tissue engineering and organ structure: a vascularized approach to liver and lung. Pediatr Res. 2008 May;63(5):520-6. | 05/2008 | Pediatr Res | |
| Blood | Wang Y, Yabuuchi A, McKinney-Freeman S, Ducharme DM, Ray MK, Chawengsaksophak K, Archer TK, Daley GQ. Cdx gene deficiency compromises embryonic hematopoiesis in the mouse. Proc Natl Acad Sci USA. 2008 Jun 3;105(22):7756-61. Epub 2008 May 29. | 05/2008 | Proc Natl Acad Sci USA | |
| Blood | Cao YA, Wagers AJ, Karsunky H, Zhao H, Reeves R, Wong RJ, Stevenson DK, Weissman IL, Contag CH. Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors. Blood. 2008 May 28. [Epub ahead of print] | 05/2008 | Blood | |
| Blood | Orford K, Kharchenko P, Lai W, Dao MC, Worhunsky DJ, Ferro A, Janzen V, Park PJ, Scadden DT. Differential H3K4 methylation identifies developmentally poised hematopoietic genes. Dev Cell. 2008 May;14(5):798-809. | 05/2008 | Dev Cell | |
| Blood | Mayack SR, Wagers AJ. Osteolineage niche cells initiate hematopoietic stem cell mobilization. Blood. 2008 May 2. [Epub ahead of print] | 05/2008 | Blood | |
| Blood | Fernandez L, Rodriguez S, Huang H, Chora A, Fernandes J, Mumaw C, Cruz E, Pollok K, Cristina F, Price JE, Ferkowicz MJ, Scadden DT, Clauss M, Cardoso AA, Carlesso N. Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation. Exp Hematol. 2008 May;36(5):545-558. | 05/2008 | Exp Hematol | |
| Cancer | Ito K, Bernardi R, Morotti A, Matsuoka S, Saglio G, Ikeda Y, Rosenblatt J, Avigan DE, Teruya-Feldstein J, Pandolfi PP. PML targeting eradicates quiescent leukaemia-initiating cells. Nature. 2008 May 11. [Epub ahead of print] | 05/2008 | Nature | |
| Cancer | Wittner BS, Sgroi DC, Ryan PD, Bruinsma TJ, Glas AM, Male A, Dahiya S, Habin K, Bernards R, Haber DA, Van't Veer LJ, Ramaswamy S. Analysis of the MammaPrint Breast Cancer Assay in a Predominantly Postmenopausal Cohort. Clin Cancer Res. 2008 May 15;14(10):2988-2993. | 05/2008 | Clin Cancer Res | |
| Cancer | Xu L, Shen SS, Hoshida Y, Subramanian A, Ross K, Brunet JP, Wagner SN, Ramaswamy S, Mesirov JP, Hynes RO. Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases. Mol Cancer Res. 2008 May;6(5):760-9. | 05/2008 | Mol Cancer Res | |
| Developmental Biology | Stadtfeld M, Brennand K, Hochedlinger K. Reprogramming of Pancreatic beta Cells into Induced Pluripotent Stem Cells. Curr Biol. 2008 May 21. [Epub ahead of print] | 05/2008 | Curr Biol | |
| Developmental Biology | Damiani D, Alexander JJ, O'Rourke JR, McManus M, Jadhav AP, Cepko CL, Hauswirth WW, Harfe BD, Strettoi E. Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina. J Neurosci. 2008 May 7;28(19):4878-87. | 05/2008 | J Neurosci | |
| Diabetes | Inada A, Kanamori H, Arai H, Akashi T, Araki M, Weir GC, Fukatsu A. A model for diabetic nephropathy: advantages of the inducible cAMP early repressor transgenic mouse over the streptozotocin-induced diabetic mouse. J Cell Physiol. 2008 May;215(2):383-91. | 05/2008 | J Cell Physiol | |
| Genetics and Genomics | Nygaard V, Liu F, Holden M, Kuo WP, Trimarchi J, Ohno-Machado L, Cepko C, Frigessi A, Glad IK, van de Wiel MA, Hovig E, Lyng H. Validation of oligoarrays for quantitative exploration of the transcriptome. BMC Genomics. 2008 May 30;9(1):258. [Epub ahead of print] | 05/2008 | BMC Genomics | |
| Genetics and Genomics | Pawlisz AS, Mutch C, Wynshaw-Boris A, Chenn A, Walsh CA, Feng Y. Lis1-Nde1 dependent neuronal fate control determines cerebral cortical size and lamination. Hum Mol Genet. 2008 May 10. [Epub ahead of print] | 05/2008 | Hum Mol Genet | |
| Imaging | Shaw SY, Westly EC, Pittet MJ, Subramanian A, Schreiber SL, Weissleder R. Perturbational profiling of nanomaterial biologic activity. Proc Natl Acad Sci USA. 2008 May 27;105(21):7387-92. Epub 2008 May 20. | 05/2008 | Proc Natl Acad Sci USA | |
| Nervous System | Li S, Jin Z, Koirala S, Bu L, Xu L, Hynes RO, Walsh CA, Corfas G, Piao X. GPR56 regulates pial basement membrane integrity and cortical lamination. J Neurosci. 2008 May 28;28(22):5817-26. | 05/2008 | J Neurosci | |
| Yang Y, Iwanaga K, Raso MG, Wislez M, Hanna AE, Wieder ED, Molldrem JJ, Wistuba II, Powis G, Demayo FJ, Kim CF, Kurie JM. Phosphatidylinositol 3-kinase mediates bronchioalveolar stem cell expansion in mouse models of oncogenic K-ras-induced lung cancer. PLoS ONE. 2008 May 21;3(5):e2220. | 05/2008 | PLoS ONE | |
| Renal System | Ichimura T, Asseldonk EJ, Humphreys BD, Gunaratnam L, Duffield JS, Bonventre JV. Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells. J Clin Invest. 2008 May;118(5):1657-68. | 05/2008 | J Clin Invest | |
| Skeletal System | Shimada M, Greer PA, McMahon AP, Bouxsein ML, Schipani E. In vivo targeted deletion of calpain small subunit, Capn4, in cells of the osteoblast lineage impairs cell proliferation, differentiation, and bone formation. J Biol Chem. 2008 May 30. [Epub ahead of print] | 05/2008 | J Biol Chem | |
| Translational Medicine | Szentirmai O, Baker CH, Bullain SS, Lin N, Takahashi M, Folkman J, Mulligan RC, Carter BS. Successful inhibition of intracranial human glioblastoma multiforme xenograft growth via systemic adenoviral delivery of soluble endostatin and soluble vascular endothelial growth factor receptor-2: laboratory investigation. J Neurosurg. 2008 May;108(5):979-88. | 05/2008 | J Neurosurg | |
| Bonventre JV. Dialysis in Acute Kidney Injury -- More Is Not Better. N Engl J Med. 2008 May 20. | 05/2008 | N Engl J Med | |
| Tissue Engineering | Rocha FG, Sundback CA, Krebs NJ, Leach JK, Mooney DJ, Ashley SW, Vacanti JP, Whang EE. The effect of sustained delivery of vascular endothelial growth factor on angiogenesis in tissue-engineered intestine. Biomaterials. 2008 Jul;29(19):2884-90. Epub 2008 Apr 8. | 04/2008 | Biomaterials | |
| Nervous System | Wernig M, Zhao JP, Pruszak J, Hedlund E, Fu D, Soldner F, Broccoli V, Constantine-Paton M, Isacson O, Jaenisch R. Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proc Natl Acad Sci USA. 2008 Apr 15;105(15):5856-61. Epub 2008 Apr 7. | 04/2008 | Proc Natl Acad Sci USA | |
| Nervous System | Mendez I, Vinuela A, Astradsson A, Mukhida K, Hallett P, Robertson H, Tierney T, Holness R, Dagher A, Trojanowski JQ, Isacson O. Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years. Nat Med. 2008 May;14(5):507-9. Epub 2008 Apr 6. | 04/2008 | Nat Med | |
| Renal System | Zhang J, Brown RP, Shaw M, Vaidya VS, Zhou Y, Espandiari P, Sadrieh N, Stratmeyer M, Keenan J, Kilty CG, Bonventre JV, Goering PL. Immunolocalization of Kim-1, RPA-1, and RPA-2 in Kidney of Gentamicin-, Mercury-, or Chromium-Treated Rats: Relationship to Renal Distributions of iNOS and Nitrotyrosine. Toxicol Pathol. 2008 Apr 25. | 04/2008 | Toxicol Pathol | |
| Review and Commentary | Weissleder R, Pittet MJ. Imaging in the era of molecular oncology. Nature. 2008 Apr 3;452(7187):580-9. Review. | 04/2008 | Nature | |
| Review and Commentary | Martin-Puig S, Wang Z, Chien KR. Lives of a heart cell: tracing the origins of cardiac progenitors. Cell Stem Cell. 2008 Apr 10;2(4):320-31. | 04/2008 | Cell Stem Cell | |
| Review and Commentary | Wang Y, Armstrong SA. Cancer: inappropriate expression of stem cell programs? Cell Stem Cell. 2008 Apr 10;2(4):297-9. | 04/2008 | Cell Stem Cell | |
| Review and Commentary | Koh I, Hong R, Weissleder R, Josephson L. Sensitive NMR Sensors Detect Antibodies to Influenza. Angew Chem Int Ed Eng. 2008 Apr 21;47(22):4119-4121. No abstract available. | 04/2008 | Angew Chem Int Ed Eng | |
| Review and Commentary | Punzo C, Cepko CL. Ultrasound-guided in utero injections allow studies of the development and function of the eye. Dev Dyn. 2008 Apr;237(4):1034-42. | 04/2008 | Dev Dyn | |
| Review and Commentary | Papayannopoulou T, Scadden DT. Stem-cell ecology and stem cells in motion. Blood. 2008 Apr 15;111(8):3923-30. | 04/2008 | Blood | |
| Review and Commentary | Williams DA. Foamy virus vectors come of age. Mol Ther. 2008 Apr;16(4):635-6. No abstract available. | 04/2008 | Mol Ther | |
| Blood | Min IM, Pietramaggiori G, Kim FS, Passegue E, Stevenson KE, Wagers AJ. The transcription factor EGR1 controls both the proliferation and localization of hematopoietic stem cells. Cell Stem Cell. 2008 Apr 10;2(4):380-91. | 04/2008 | Cell Stem Cell | |
| Blood | Muller LU, Milsom MD, Kim MO, Schambach A, Schuesler T, Williams DA. Rapid Lentiviral Transduction Preserves the Engraftment Potential of Fanca(-/-) Hematopoietic Stem Cells. Mol Ther. 2008 Apr 8. | 04/2008 | Mol Ther | |
| Cancer | Kirstetter P, Schuster MB, Bereshchenko O, Moore S, Dvinge H, Kurz E, Theilgaard-Monch K, Mansson R, Pedersen TA, Pabst T, Schrock E, Porse BT, Jacobsen SE, Bertone P, Tenen DG, Nerlov C. Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells. Cancer Cell. 2008 Apr;13(4):299-310. | 04/2008 | Cancer Cell | |
| Cancer | Wernig G, Kharas MG, Okabe R, Moore SA, Leeman DS, Cullen DE, Gozo M, McDowell EP, Levine RL, Doukas J, Mak CC, Noronha G, Martin M, Ko YD, Lee BH, Soll RM, Tefferi A, Hood JD, Gilliland DG. Efficacy of TG101348, a selective JAK2 inhibitor, in treatment of a murine model of JAK2V617F-induced polycythemia vera. Cancer Cell. 2008 Apr;13(4):311-20. | 04/2008 | Cancer Cell | |
| Cancer | Austin KM, Gupta ML, Coats SA, Tulpule A, Mostoslavsky G, Balazs AB, Mulligan RC, Daley G, Pellman D, Shimamura A. Mitotic spindle destabilization and genomic instability in Shwachman-Diamond syndrome. J Clin Invest. 2008 Apr;118(4):1511-8. | 04/2008 | J Clin Invest | |
| Cancer | Quintas-Cardama A, Tong W, Manshouri T, Vega F, Lennon PA, Cools J, Gilliland DG, Lee F, Cortes J, Kantarjian H, Garcia-Manero G. Activity of tyrosine kinase inhibitors against human NUP214-ABL1-positive T cell malignancies. Leukemia. 2008 Apr 10. | 04/2008 | Leukemia | |
| Cell Biology | Saharinen P, Eklund L, Miettinen J, Wirkkala R, Anisimov A, Winderlich M, Nottebaum A, Vestweber D, Deutsch U, Koh GY, Olsen BR, Alitalo K. Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts. Nat Cell Biol. 2008 May;10(5):527-37. Epub 2008 Apr 20. | 04/2008 | Nat Cell Biol | |
| Developmental Biology | Wu X, Tu X, Joeng KS, Hilton MJ, Williams DA, Long F. Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling. Cell. 2008 Apr 18;133(2):340-53. Read Abstract. | 04/2008 | Cell | |
| Developmental Biology | Wang J, Levasseur DN, Orkin SH. Requirement of Nanog dimerization for stem cell self-renewal and pluripotency. Proc Natl Acad Sci USA. 2008 Apr 29;105(17):6326-31. Epub 2008 Apr 24. | 04/2008 | Proc Natl Acad Sci USA | |
| Developmental Biology | Sue N, Jack BH, Eaton SA, Pearson RC, Funnell AP, Turner J, Czolij R, Denyer G, Bao S, Molero-Navajas JC, Perkins A, Fujiwara Y, Orkin SH, Bell-Anderson K, Crossley M. Targeted disruption of the Basic Kruppel-like Factor (Klf3) gene reveals a role in adipogenesis. Mol Cell Biol. 2008 Apr 7. | 04/2008 | Mol Cell Biol | |
| Developmental Biology | Kim DS, Ross SE, Trimarchi JM, Aach J, Greenberg ME, Cepko CL. Identification of molecular markers of bipolar cells in the murine retina. J Comp Neurol. 2008 Apr 10;507(5):1795-810. | 04/2008 | J Comp Neurol | |
| Diabetes | Cha HC, Oak NR, Kang S, Tran TA, Kobayashi S, Chiang SH, Tenen DG, Macdougald OA. Phosphorylation of C/EBPalpha regulates GLUT4 expression and glucose transport in adipocytes. J Biol Chem. 2008 Apr 11. | 04/2008 | J Biol Chem | |
| Imaging | Shah K, Hingtgen S, Kasmieh R, Figueiredo JL, Garcia-Garcia E, Martinez-Serrano A, Breakefield X, Weissleder R. Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model. J Neurosci. 2008 Apr 23;28(17):4406-13. | 04/2008 | J Neurosci | |
| Imaging | Kelly KA, Bardeesy N, Anbazhagan R, Gurumurthy S, Berger J, Alencar H, Depinho RA, Mahmood U, Weissleder R. Targeted nanoparticles for imaging incipient pancreatic ductal adenocarcinoma. PLoS Med. 2008 Apr 15;5(4):e85. | 04/2008 | PLoS Med | |
| Imaging | Kelly KA, Setlur SR, Ross R, Anbazhagan R, Waterman P, Rubin MA, Weissleder R. Detection of early prostate cancer using a hepsin-targeted imaging agent. Cancer Res. 2008 Apr 1;68(7):2286-91. | 04/2008 | Cancer Res | |
| Muscular System | Luth ES, Jun SJ, Wessen MK, Liadaki K, Gussoni E, Kunkel LM. Bone marrow side population cells are enriched for progenitors capable of myogenic differentiation. J Cell Sci. 2008 May 1;121(Pt 9):1426-34. Epub 2008 Apr 8. | 04/2008 | J Cell Sci | |
| Nervous System | Wang X, Liu J, Zhu H, Tejima E, Tsuji K, Murata Y, Atochin DN, Huang PL, Zhang C, Lo EH. Effects of Neuroglobin Overexpression on Acute Brain Injury and Long-Term Outcomes After Focal Cerebral Ischemia. Stroke. 2008 Apr 10. | 04/2008 | Stroke | |
| Nervous System | Kohno T, Wang H, Amaya F, Brenner GJ, Cheng JK, Ji RR, Woolf CJ. Bradykinin enhances AMPA and NMDA receptor activity in spinal cord dorsal horn neurons by activating multiple kinases to produce pain hypersensitivity. J Neurosci. 2008 Apr 23;28(17):4533-40. | 04/2008 | J Neurosci | |
| Nervous System | Lagali PS, Balya D, Awatramani GB, Munch TA, Kim DS, Busskamp V, Cepko CL, Roska B. Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration. Nat Neurosci. 2008 Apr 27. | 04/2008 | Nat Neurosci | |
| Nervous System | Hedlund EM, Pruszak J, Lardaro T, Ludwig W, Vi̱uela A, Kim KS, Isacson O. Embryonic Stem (ES) Cell-derived Pitx3-eGFP Midbrain Dopamine Neurons Survive Enrichment by FACS and Function in an Animal Model of Parkinson's Disease. Stem Cells. 2008 Apr 3. | 04/2008 | Stem Cells | |
| Review and Commentary | Ferguson MA, Vaidya VS, Bonventre JV. Biomarkers of nephrotoxic acute kidney injury. Toxicology. 2008 Mar 20;245(3):182-93. Epub 2008 Jan 4. | 03/2008 | Toxicology | |
| Review and Commentary | Li Q, Gregory RI. MicroRNA Regulation of Stem Cell Fate. Cell Stem Cell. 2008 Mar 6;2(3):195-6. | 03/2008 | Cell Stem Cell | |
| Review and Commentary | de Koning EJ, Bonner-Weir S, Rabelink TJ. Preservation of beta-cell function by targeting beta-cell mass. Trends Pharmacol Sci. 2008 Mar 20. | 03/2008 | Trends Pharmacol Sci | |
| Review and Commentary | Kreidberg JA. Integrins and matrix in the glomerulus: old mysteries and new insights. J Am Soc Nephrol. 2008 Apr;19(4):650-1. Epub 2008 Mar 5. | 03/2008 | J Am Soc Nephrol | |
| Review and Commentary | Wingert RA, Davidson AJ. The zebrafish pronephros: A model to study nephron segmentation. Kidney Int. 2008 Mar 5. | 03/2008 | Kidney Int | |
| Review and Commentary | Karra R, Wu SM. Multipotent stem cells in cardiac regenerative therapy. Regen Med. 2008 Mar;3(2):189-98. | 03/2008 | Regen Med | |
| Review and Commentary | Williams DA. NIH recombinant DNA Advisory Committee continues to ponder adverse event associated with AAV gene therapy trial. Mol Ther. 2008 Mar;16(3):427-8. | 03/2008 | Mol Ther | |
| Review and Commentary | Lock EA, Bonventre JV. Biomarkers in translation; past, present and future. Toxicology. 2008 Mar 20;245(3):163-6. Epub 2007 Dec 17. | 03/2008 | Toxicology | |
| Review and Commentary | Scadden DT. Circadian rhythms: stem cells traffic in time. Nature. 2008 Mar 27;452(7186):416-7. | 03/2008 | Nature | |
| Blood | Chae HD, Lee KE, Williams DA, Gu Y. Cross-talk between RhoH and Rac1 in regulation of actin cytoskeleton and chemotaxis of hematopoietic progenitor cells. Blood. 2008 Mar 1;111(5):2597-605. Epub 2007 Dec 18. | 03/2008 | Blood | |
| Blood | Pardanani A, Fridley BL, Lasho TL, Gilliland DG, Tefferi A. Host genetic variation contributes to phenotypic diversity in myeloproliferative disorders. Blood. 2008 Mar 1;111(5):2785-9. Epub 2007 Nov 15. | 03/2008 | Blood | |
| Blood | Fleming HE, Janzen V, Lo Celso C, Guo J, Leahy KM, Kronenberg HM, Scadden DT. Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo. Cell Stem Cell. 2008 Mar 6;2(3):274-83. | 03/2008 | Cell Stem Cell | |
| Blood | Rhodes KE, Gekas C, Wang Y, Lux CT, Francis CS, Chan DN, Conway S, Orkin SH, Yoder MC, Mikkola HK. The emergence of hematopoietic stem cells is initiated in the placental vasculature in the absence of circulation. Cell Stem Cell. 2008 Mar 6;2(3):252-63. | 03/2008 | Cell Stem Cell | |
| Blood | Jia Y, Loison F, Hattori H, Li Y, Erneux C, Park SY, Gao C, Chai L, Silberstein LE, Schurmans S, Luo HR. Inositol trisphosphate 3-kinase B (InsP3KB) as a physiological modulator of myelopoiesis. Proc Natl Acad Sci USA. 2008 Mar 25;105(12):4739-44. Epub 2008 Mar 13. | 03/2008 | Proc Natl Acad Sci USA | |
| Blood | Austin KM, Gupta ML, Coats SA, Tulpule A, Mostoslavsky G, Balazs AB, Mulligan RC, Daley G, Pellman D, Shimamura A. Mitotic spindle destabilization and genomic instability in Shwachman-Diamond syndrome. J Clin Invest. 2008 Mar 6. | 03/2008 | J Clin Invest | |
| Renal System | Humphreys BD, Valerius MT, Kobayashi A, Mugford JW, Soeung S, Duffield JS, McMahon AP, Bonventre JV. Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell. 2008 Mar 6;2(3):284-91. | 03/2008 | Cell Stem Cell | |
| Renal System | Zhang PL, Rothblum LI, Han WK, Blasick TM, Potdar S, Bonventre JV. Kidney injury molecule-1 expression in transplant biopsies is a sensitive measure of cell injury. Kidney Int. 2008 Mar;73(5):608-14. Epub 2007 Dec 26. | 03/2008 | Kidney Int | |
| Developmental Biology | Stadtfeld M, Maherali N, Breault DT, Hochedlinger K. Defining Molecular Cornerstones during Fibroblast to iPS Cell Reprogramming in Mouse. Cell Stem Cell. 2008 Mar 6;2(3):230-40. Epub 2008 Feb 14. | 03/2008 | Cell Stem Cell | |
| Developmental Biology | Tullet JM, Hertweck M, An JH, Baker J, Hwang JY, Liu S, Oliveira RP, Baumeister R, Blackwell TK. Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans. Cell. 2008 Mar 21;132(6):1025-38. | 03/2008 | Cell | |
| Developmental Biology | Punzo C, Cepko CL. Ultrasound-guided in utero injections allow studies of the development and function of the eye. Dev Dyn. 2008 Mar 19;237(4):1034-1042 [Epub ahead of print] | 03/2008 | Dev Dyn | |
| Developmental Biology | Narala SR, Allsopp RC, Wells TB, Zhang G, Prasad P, Coussens MJ, Rossi DJ, Weissman IL, Vaziri H. SIRT1 Acts as a Nutrient-sensitive Growth Suppressor and Its Loss Is Associated with Increased AMPK and Telomerase Activity. Mol Biol Cell. 2008 Mar;19(3):1210-9. Epub 2008 Jan 9. | 03/2008 | Mol Biol Cell | |
| Developmental Biology | Rajagopal J, Carroll TJ, Guseh JS, Bores SA, Blank LJ, Anderson WJ, Yu J, Zhou Q, McMahon AP, Melton DA. Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme. Development. 2008 Mar 26. | 03/2008 | Development | |
| Developmental Biology | Kim J, Chu J, Shen X, Wang J, Orkin SH. An extended transcriptional network for pluripotency of embryonic stem cells. Cell. 2008 Mar 21;132(6):1049-61. | 03/2008 | Cell | |
| Developmental Biology | Paulsen FP, Woon CW, Varoga D, Jansen A, Garreis F, Jäger K, Amm M, Podolsky DK, Steven P, Barker NP, Sel S. ITF/TFF3 promotes re-epithelialization of corneal wounds. J Biol Chem. 2008 Mar 7. | 03/2008 | J Biol Chem | |
| Developmental Biology | Puschendorf M, Terranova R, Boutsma E, Mao X, Isono K, Brykczynska U, Kolb C, Otte AP, Koseki H, Orkin SH, van Lohuizen M, Peters AH. PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos. Nat Genet. 2008 Apr;40(4):411-20. Epub 2008 Mar 2. | 03/2008 | Nat Genet | |
| Cancer | Lasho TL, Tefferi A, Hood JD, Verstovsek S, Gilliland DG, Pardanani A. TG101348, a JAK2-selective antagonist, inhibits primary hematopoietic cells derived from myeloproliferative disorder patients with JAK2V617F, MPLW515K or JAK2 exon 12 mutations as well as mutation negative patients. Leukemia. 2008 Mar 20. | 03/2008 | Leukemia | |
| Cancer | Thomas EK, Cancelas JA, Zheng Y, Williams DA. Rac GTPases as key regulators of p210-BCR-ABL-dependent leukemogenesis. Leukemia. 2008 Mar 20. | 03/2008 | Leukemia | |
| Cancer | Swanson KD, Winter JM, Reis M, Bentires-Alj M, Greulich H, Grewal R, Hruban RH, Yeo CJ, Yassin Y, Iartchouk O, Montgomery K, Whitman SP, Caligiuri MA, Loh ML, Gilliland DG, Look AT, Kucherlapati R, Kern SE, Meyerson M, Neel BG. SOS1 mutations are rare in human malignancies: implications for Noonan Syndrome patients. Genes Chromosomes Cancer. 2008 Mar;47(3):253-9. | 03/2008 | Genes Chromosomes Cancer | |
| Cancer | Langenau DM, Keefe MD, Storer NY, Jette CA, Smith AC, Ceol CJ, Bourque C, Look AT, Zon LI. Co-injection strategies to modify radiation sensitivity and tumor initiation in transgenic Zebrafish. Oncogene. 2008 Mar 17. | 03/2008 | Oncogene | |
| Cancer | Costa DB, Schumer ST, Tenen DG, Kobayashi S. Differential responses to erlotinib in epidermal growth factor receptor (EGFR)-mutated lung cancers with acquired resistance to gefitinib carrying the L747S or T790M secondary mutations. J Clin Oncol. 2008 Mar 1;26(7):1182-4; author reply 1184-6. No abstract available. | 03/2008 | J Clin Oncol | |
| Technology | Osafune K, Caron L, Borowiak M, Martinez RJ, Fitz-Gerald CS, Sato Y, Cowan CA, Chien KR, Melton DA. Marked differences in differentiation propensity among human embryonic stem cell lines. Nat Biotechnol. 2008 Mar;26(3):313-5. Epub 2008 Feb 17. | 03/2008 | Nat Biotechnol | |
| Technology | Shin M, Abukawa H, Troulis MJ, Vacanti JP. Development of a biodegradable scaffold with interconnected pores by heat fusion and its application to bone tissue engineering. J Biomed Mater Res A. 2008 Mar 1;84(3):702-9. | 03/2008 | J Biomed Mater Res A | |
| Technology | Deutsch EW, Ball CA, Berman JJ, Bova GS, Brazma A, Bumgarner RE, Campbell D, Causton HC, Christiansen JH, Daian F, Dauga D, Davidson DR, Gimenez G, Goo YA, Grimmond S, Henrich T, Herrmann BG, Johnson MH, Korb M, Mills JC, Oudes AJ, Parkinson HE, Pascal LE, Pollet N, Quackenbush J, Ramialison M, Ringwald M, Salgado D, Sansone SA, Sherlock G, Stoeckert CJ Jr, Swedlow J, Taylor RC, Walashek L, Warford A, Wilkinson DG, Zhou Y, Zon LI, Liu AY, True LD. Minimum information specification for in situ hybridization and immunohistochemistry experiments (MISFISHIE). Nat Biotechnol. 2008 Mar;26(3):305-12. | 03/2008 | Nat Biotechnol | |
| Cardiovascular System | Chan JY, Takeda M, Briggs LE, Graham ML, Lu JT, Horikoshi N, Weinberg EO, Aoki H, Sato N, Chien KR, Kasahara H. Identification of cardiac-specific myosin light chain kinase. Circ Res. 2008 Mar 14;102(5):571-80. Epub 2008 Jan 17. | 03/2008 | Circ Res | |
| Cardiovascular System | Kontaridis MI, Yang W, Bence KK, Cullen D, Wang B, Bodyak N, Ke Q, Hinek A, Kang PM, Liao R, Neel BG. Deletion of Ptpn11 (Shp2) in cardiomyocytes causes dilated cardiomyopathy via effects on the extracellular signal-regulated kinase/mitogen-activated protein kinase and RhoA signaling pathways. Circulation. 2008 Mar 18;117(11):1423-35. Epub 2008 Mar 3. | 03/2008 | Circulation | |
| Diabetes | Marselli L, Thorne J, Ahn YB, Omer A, Sgroi DC, Libermann T, Otu HH, Sharma A, Bonner-Weir S, Weir GC. Gene Expression of Purified {beta}-Cell Tissue Obtained from Human Pancreas with Laser Capture Microdissection. J Clin Endocrinol Metab. 2008 Mar;93(3):1046-53. Epub 2007 Dec 11. | 03/2008 | J Clin Endocrinol Metab | |
| Imaging | Hong R, Cima MJ, Weissleder R, Josephson L. Magnetic microparticle aggregation for viscosity determination by MR. Magn Reson Med. 2008 Mar;59(3):515-20. | 03/2008 | Magn Reson Med | |
| Imaging | Guimaraes AR, Tabatabei S, Dahl D, McDougal WS, Weissleder R, Harisinghani MG. Pilot Study Evaluating Use of Lymphotrophic Nanoparticle-Enhanced Magnetic Resonance Imaging for Assessing Lymph Nodes in Renal Cell Cancer. Urology. 2008 Mar 4. | 03/2008 | Urology | |
| Imaging | Figueiredo JL, Passerotti CC, Sponholtz T, Nguyen HT, Weissleder R. A novel method of imaging calcium urolithiasis using fluorescence. J Urol. 2008 Apr;179(4):1610-4. Epub 2008 Mar 4. | 03/2008 | J Urol | |
| Imaging | Sosnovik DE, Nahrendorf M, Weissleder R. Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications. Basic Res Cardiol. 2008 Mar;103(2):122-30. | 03/2008 | Basic Res Cardiol | |
| Imaging | Nahrendorf M, Sosnovik DE, Weissleder R MR-optical imaging of cardiovascular molecular targets. Basic Res Cardiol. 2008 Mar;103(2):87-94. | 03/2008 | Basic Res Cardiol | |
| Immunology | Jakubzick C, Tacke F, Ginhoux F, Wagers AJ, van Rooijen N, Mack M, Merad M, Randolph GJ. Blood Monocyte Subsets Differentially Give Rise to CD103+ and CD103- Pulmonary Dendritic Cell Populations. J Immunol. 2008 Mar 1;180(5):3019-27. | 03/2008 | J Immunol | |
| Pulmonary System | Demchenko IT, Atochin DN, Gutsaeva DR, Godfrey RR, Huang PL, Piantadosi CA, Allen BW. Contributions of Nitric Oxide Synthase Isoforms to Pulmonary Oxygen Toxicity, Local vs. Mediated Effects. Am J Physiol Lung Cell Mol Physiol. 2008 Mar 7. | 03/2008 | Am J Physiol Lung Cell Mol Physiol | |
| Review and Commentary | Daley GQ, Hyun I, Lindvall O. Mapping the Road to the Clinical Translation of Stem Cells. ISSCR: Committee Forum. Mapping the Road to the Clinical Translation of Stem Cells. Cell Stem Cell. 2008 Feb 7;2(2):139-140. | 02/2008 | Cell Stem Cell | |
| Review and Commentary | McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P; for the GUDMAP project. GUDMAP: The Genitourinary Developmental Molecular Anatomy Project. J Am Soc Nephrol. 2008 Feb 20. | 02/2008 | J Am Soc Nephrol | |
| Review and Commentary | Orkin SH, Zon LI. Hematopoiesis: an evolving paradigm for stem cell biology. Cell. 2008 Feb 22;132(4):631-44. | 02/2008 | Cell |
