Seed Grants

The purpose of HSCI Seed Grants is to provide early funding for innovative projects in any field of stem cell research. The awards put particular emphasis on projects that might be difficult to fund from other sources, either because a project is considered to be "high risk/high reward" or because the research is ineligible for federal funding under the current federal restrictions on human embryonic stem cell research. Seed grants are open to any investigator with a Harvard affiliation.

For the seventh consecutive year, HSCI awarded seed grants to scientists throughout the HSCI community to provide critical early funding for stem cell research. In 2011, 10 seed grants totaling $1.8 million were awarded to investigators selected from a large pool of applicants across HSCI-affiliated institutions.

This year’s grants will support stem cell research in a variety of targeted disease areas such as cancer, kidney and skeletal diseases.  The grants will also support research of broadly applicable areas of stem cell biology such as cell development, bio/tissue engineering and self-renewal.  This year, for the first time, applications were reviewed in Basic Research or Translational categories, and as a result we were able to fund a translational project focused on engineered fascia for stem cell therapy in hernia repair.

Click to view seed grant recipients from previous years: 2010 | 2009 | 2008 | 2007 | 2006 | 2005

2011 Seed Grant Recipients

Project Lead Affiliation Title  
Wolfram Goessling, MD, PhD Brigham and Women's Hospital Functional characterization of genes associated with abnormal liver tests for liver development and repair – a post-GWAS approach  
Stanley Shaw, MD, PhD Massachusetts General Hospital Small molecule inhibitors of p16INK4a: proof-of-concept for the generation of iPS cells via a high-throughput screening platform  
Carla F. Kim, PhD Children's Hospital Boston Imprinted gene regulation in lung and skin stem cell self-renewal  
Elliot Chaikof, MD, PhD Beth Israel Deaconess Medical Center Engineered fascia for stem cell therapy in hernia repair  
Rakesh Karmacharya, MD, PhD McLean Hospital Identification of cellular signatures for schizophrenia in iPSC-derived neuronal cells  
Sandra McAllister, PhD Brigham and Women's Hospital Understanding how systemic factors govern breast cancer stem cell plasticity and malignancy  
Chien-Wei (Eric) Liao, MD, PhD Massachusetts General Hospital Transcriptome and functional analysis of neural crest stem cell  
Xu Wu, PhD Massachusetts General Hospital Controlling stem cell self-renewal and differentiation using small molecule modulators of hippo signaling pathway  
Jordan A. Kreidberg, MD Children's Hospital Boston Reprogramming ES and IPS cells into kidney progenitor cells  
Joy Wu, MD, PhD Massachusetts General Hospital Chemical screening of pluripotent stem cells for modifiers of mesenchymal lineage commitment