“Good” cells can go “bad” in a “bad neighborhood"

HSCI Co-Director David Scadden, MD, report that normal blood stem cells “are dependent upon their environment. They get their cues from the surrounding ‘neighborhood’ of bone cells.”

March 22, 2010

The general theory of cancer development holds that malignancies occur because of the presence of certain genetic elements within the affected cells.

But a new study by Harvard researchers at Massachusetts General Hospital (MGH) indicates that “good” cells can become cancerous because of exposure to a “bad” environment within the body — similarly to the way a “good boy” may turn to crime when exposed to the pressures of life in a crime-ridden neighborhood.

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