IPS Core

The HSCI iPS Core facility was created to accelerate research in the stem cell field by facilitating the derivation and distribution of iPS cell lines. Disease-specific iPS lines provide us with a unique opportunity to study the mechanisms of disease and ultimately to develop new treatments. The iPS Core serves as a repository for iPS cells produced by HSCI scientists and functions as a laboratory to produce disease-specific lines for sharing with the HSCI and broader research community.

Human Pluripotent Stem Cell Lines Available

Lines from Harvard University:

For available hESC lines see http://stemcelldistribution.harvard.edu/

For available iPS lines see http://stemcelldistribution.harvard.edu/

Lines from Boston Children’s Hospital:

iPS line	Disease/control	Sex	Source of cells	Transduction system	Request form	Scientific paper
hFib2-iPS4	Healthy donor control	Male	Fibroblasts	Retrovirus 4 factors: OSKM	Download and email to Judit.Totth@childrens.harvard.edu	Paper
hFib2-iPS5	Healthy donor control	Male	Fibroblasts	Retrovirus 4 factors: OSKM	Download and email to Judit.Totth@childrens.harvard.edu	Paper
ADA-iPS3	ADA/SCID	Male	Fibroblasts Coriell: GM01390	Retrovirus 3 factors: OSK	Download and email to Judit.Totth@childrens.harvard.edu	Paper
BMD-iPS1	Becker Duchenne muscular dystrophy	Male	Fibroblasts Coriell: GM04569	Retrovirus 4 factors: OSKM	Download and email to Judit.Totth@childrens.harvard.edu	Paper
DS1-iPS4	Down Syndrome	Male	Fibroblasts Coriell: AG05397	Retrovirus 4 factors: OSKM	Download and email to Judit.Totth@childrens.harvard.edu	Paper
DS2-iPS10	Down Syndrome		ATCC		Download and email to Judit.Totth@childrens.harvard.edu
HD1-iPS1	Huntington disease	Female	Fibroblasts Coriell: GM04281	Retrovirus 4 factors: OSKM	Download and email to Judit.Totth@childrens.harvard.edu	Paper
HD1-iPS4	Huntington disease	Female	Fibroblasts Coriell: GM04281	Retrovirus 4 factors: OSKM	Download and email to Judit.Totth@childrens.harvard.edu	Paper
JDM-iPS1	Diabetes Mellitus Juvenile	Female	Fibroblasts Coriell: GM02416	Retrovirus 3 factors: OSK	Download and email to Judit.Totth@childrens.harvard.edu	Paper
JDM-iPS10	Diabetes Mellitus Juvenile	Female	Fibroblasts Coriell: GM02416	Retrovirus 4 factors: OSKM	Download and email to Judit.Totth@childrens.harvard.edu	Paper
PD-iPS1	Parkinson’s disease	Male	Fibroblasts Coriell: AG20446	Retrovirus 4 factors: OSKM	Download and email to Judit.Totth@childrens.harvard.edu	Paper
PD-iPS5	Parkinson’s disease		Coriell		Download and email to Judit.Totth@childrens.harvard.edu
PD-iPS11	Parkinson’s disease	Male	Fibroblasts Coriell: AG20446	Retrovirus 4 factors: OSKM	Download and email to Judit.Totth@childrens.harvard.edu	Paper
SBDS-iPS2	Shwachman-Bodian-Diamond syndrome	Male	Mesenchymal stem cells	Retrovirus 4 factors: OSKM	Download and email to Judit.Totth@childrens.harvard.edu	Paper
SBDS-iPS3	Shwachman-Bodian-Diamond syndrome	Male	Mesenchymal stem cells	Retrovirus 4 factors: OSKM	Download and email to Judit.Totth@childrens.harvard.edu	Paper
GD iPS1	Gaucher disease		Coriell		Download and email to Judit.Totth@childrens.harvard.edu
DMD-iPS1	Duchenne muscular dystrophy		Coriell		Download and email to Judit.Totth@childrens.harvard.edu
DMD-iPS2	Duchenne muscular dystrophy		Coriell		Download and email to Judit.Totth@childrens.harvard.edu